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  • Basic Info
Licensed from
Generic: Coriolus
treats Leukemia, Non-small cell lung cancer, Nasopharyngeal carcinoma, Esophageal cancer, Liver cancer, Colorectal cancer, Breast cancer, Gastric cancer, and Lung cancer
               



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Interactions

Interactions with Drugs

Liver function impairment and toxicity has been reported. Caution is advised when taking PSK with other agents that are broken down by the liver due to increased risk of side effects.

Antiangiogenic properties (inhibition new blood vessel growth) have been proposed. In theory, there could be an additive effect when PSK is taken in conjugation with other known antiangiogenic agents, such as leflunomide.

Thrombocytopenia (low blood platelet count) has been reported. Theoretically, this could increase the risk of bleeding. Leukopenia and albuminuria were also observed in two clinical trials. It should be noted that patients also received chemotherapy in addition to PSK in these trials. These effects may be attributed to either PSK or chemotherapy.

Numerous animal and human studies have demonstrated that PSK may improve survival time in patients with lung cancer, gastric cancer, stomach cancer, colon cancer, and leukemia when used in conjunction with chemotherapy. This may be a positive interaction, although additional study is needed to confirm this finding.

PSK in immunochemotherapy has been used in combination with hormone therapy to treat pancreatic cancer; therefore, additive effects are possible.

Interactions with Herbs and Dietary Supplements

Liver function impairment and toxicity has been reported. Caution is advised when taking PSK with other agents that are broken down by the liver due to increased risk of side effects.

Antiangiogenic properties (inhibition of new blood vessel growth) have been proposed. In theory, there could be an additive effect when PSK is taken in conjugation with other known antiangiogenic herbs and supplements such as shark cartilage, horse chestnut, feverfew, and bilberry.

Thrombocytopenia (low blood platelet count) has been reported. Theoretically, this could increase the risk of bleeding. Leukopenia and albuminuria were also observed in two clinical trials. It should be noted that patients also received chemotherapy in addition to PSK in these trials. These effects may be attributed to either PSK or chemotherapy.

PSK in immunochemotherapy has been used in combination with hormone therapy to treat pancreatic cancer; therefore, additive effects are possible.

Theoretically, PSK may have a synergistic effect with other immunotherapeutic herbs and supplements. Numerous animal and human studies have demonstrated PSK improves survival time in patients with lung cancer, gastric cancer, stomach cancer, colon cancer, and leukemia when used in conjunction with chemotherapy.

               
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