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  • Basic Info
Licensed from
Generic: Coleus forskohlii
treats Breathing aid for intubation, Cardiomyopathy, Glaucoma, Erectile dysfunction, Depression and schizophrenia, Asthma, Anti-inflammatory action after cardiopulmonary bypass, and Breast milk stimulant

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This information is based on a systematic review of scientific literature, and was peer- reviewed and edited by contributors to the Natural Standard Research Collaboration ( Tracee Rae Abrams, PharmD (University of Rhode Island); Chi Dam, PharmD (Northeastern University); Cathy DeFranco Kirkwood, MPH, CCCJS- MAC (MD Anderson Cancer Center); Dana A. Hackman, BS (Northeastern University); Jo Hermans, PhD (University of Leiden, the Netherlands); Tamara Milkin, PharmD (Northeastern University); Phuong Ngo, PharmD (Massachusetts College of Pharmacy); Erica Seamon, PharmD (Nova Southeastern University); Shaina Tanguay- Colucci, BS (Natural Standard Research Collaboration); Catherine Ulbricht, PharmD (Massachusetts General Hospital); Mamta Vora, PharmD (Northeastern University); Wendy Weissner, BA (Natural Standard Research Collaboration); Lisa Wendt, PharmD (Albany College of Pharmacy); Jen Woods, BS (Northeastern University).


DISCLAIMER: Natural Standard developed the above evidence- based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to Selected references are listed below.

al Sereiti MR, Abu- Amer KM, Sen P. Pharmacology of rosemary (Rosmarinus officinalis Linn.) and its therapeutic potentials. Indian J Exp Biol 1999;37(2):124- 130.

Almeida FC, Lemonica IP. The toxic effects of Coleus barbatus B. on the different periods of pregnancy in rats. J Ethnopharmacol 2000;73(1- 2):53- 60.

Bersudsky Y, Kotler M, Shifrin M, et al. A preliminary study of possible psychoactive effects of intravenous forskolin in depressed and schizophrenic patients. Short communication. J Neural Transm 1996;103(12):1463- 1467.

Bryld LE. Airborne contact dermatitis from Coleus plant. Am J Contact Dermat 1997;8(1):8- 9.

Cahn D, Melman A, Valcic M, et al. Forskolin: a promising new adjunct to intracavernous pharmacotherapy. J Urol 1996;155(5):1789- 1794.

Hayashida N, Chihara S, Tayama E, et al. Antiinflammatory effects of colforsin daropate hydrochloride, a novel water- soluble forskolin derivative. Ann Thorac Surg 2001;71(6):1931- 1938.

Ishikawa Y. Isoform- targeted regulation of cardiac adenylyl cyclase. J Cardiovasc Pharmacol 2003;41 Suppl 1:S1- S4.

Maeda H, Ozawa H, Saito T, et al. Potential antidepressant properties of forskolin and a novel water- soluble forskolin (NKH477) in the forced swimming test. Life Sci 1997;61(25):2435- 2442.

Maeda N, Tamagawa T, Niki I, et al. Increase in insulin release from rat pancreatic islets by quinolone antibiotics. Br J Pharmacol 1996;117(2):372- 376.

Mei SX, Jiang B, Niu XM, et al. Abietane diterpenoids from Coleus xanthanthus. J Nat Prod 2002;65(5):633- 637.

Mulhall JP, Daller M, Traish AM, et al. Intracavernosal forskolin: role in management of vasculogenic impotence resistant to standard 3- agent pharmacotherapy. J Urol 1997;158(5):1752- 1758.

Tewtrakul S, Miyashiro H, Nakamura N, et al. HIV- 1 integrase inhibitory substances from Coleus parvifolius. Phytother Res 2003;17(3):232- 239.

Wajima Z, Shiga T, Yoshikawa T, et al. Effect of prophylactic bronchodilator treatment with intravenous colforsin daropate, a water- soluble forskolin derivative, on airway resistance after tracheal intubation. Anesthesiology 2003;99(1):18- 26.

Yanagihara H, Sakata R, Shoyama Y, et al. Rapid analysis of small samples containing forskolin using monoclonal antibodies. Planta Med 1996;62(2):169- 172.

Yousif MH, Thulesius O. Forskolin reverses tachyphylaxis to the bronchodilator effects of salbutamol: an in- vitro study on isolated guinea- pig trachea. J Pharm Pharmacol 1999;51(2):181- 186.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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