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  • Basic Info
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Generic: Coleus
treats Breathing aid for intubation, Cardiomyopathy, Glaucoma, Erectile dysfunction, Depression and schizophrenia, Asthma, Anti-inflammatory action after cardiopulmonary bypass, and Breast milk stimulant
               



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Safety

DISCLAIMER: Many complementary techniques are practiced by healthcare professionals with formal training, in accordance with the standards of national organizations. However, this is not universally the case, and adverse effects are possible. Due to limited research, in some cases only limited safety information is available.

Allergies

Avoid in individuals with a known allergy or hypersensitivity to Coleus forskohlii and related species. Rash may occur in sensitive individuals.

Side Effects and Warnings

Coleus is generally regarded as safe, although long- term safety data are lacking. Inhalation of forskolin may cause sore throat, upper respiratory tract irritation, mild to moderate cough, tremor, or restlessness. Coleus eye drops may produce a milky covering over the eyes.

Coleus may lower blood sugar and stimulate the thyroid gland. Use cautiously in patients with thyroid disorders. Also use cautiously in diabetic patients. Colenol, a compound isolated from coleus, stimulates insulin release.

Theoretically, coleus may increase the risk of bleeding. Use cautiously in patients with a history of bleeding, hemostatic disorders or drug- related hemostatic problems. Discontinue use in patients at least two weeks prior to surgical or dental procedure, due to risk of bleeding. Avoid use in patients with active bleeding.

Use cautiously in patients with low blood pressure or those at risk for hypotension. Also use cautiously in patients with heart disease or asthma.

Avoid during pregnancy due to possibility of abortifacient (abortion inducing) effects.

Pregnancy and Breastfeeding

Coleus is not recommended in pregnant or breastfeeding women due to a lack of available scientific evidence. It is unknown if coleus is excreted in the breast milk.

Interactions

Interactions with Drugs

When used with other blooding thinning agents, such as aspirin, ibuprofen, and naproxen, coleus may increase the risk of bleeding.

Although not well studied in humans, forskolin may interact with antidepressants, antihistamines, blood pressure altering agents, asthma medications, beta- blockers, inotropic agents or thyroid medications. It may also interact with drugs used for cancer and weight loss, or drugs that are processed through the liver.

Coleus should be used cautiously when taken concurrently with agents that are dependent on pH and gastric action for breakdown and activation such as newer cephalosporin antibiotics, itraconazole, ketoconazole, and warfarin.

Although not well studied in humans, topical forskolin may significantly reduce intra- ocular pressure (IOP). When used with other medications that decrease IOP, it may result in additive effects.

Colenol, a compound isolated from coleus, stimulates insulin release and its use with blood sugaring lowering agents or exogenous insulin may result in additive effects.

Interactions with Herbs and Dietary Supplements

When used with other blooding thinning herbs or supplements, such as Ginkgo biloba and garlic, coleus may increase the risk of bleeding.

Although not well studied in humans, forskolin may interact with antidepressants, antihistamines, blood pressure altering agents, asthma agents, heart agents, inotropic agents or thyroid medications. It may also interact with herbs or supplements used for cancer and weight loss, or drugs that are processed through the liver.

Although not well studied in humans, topical forskolin may significantly reduce intra- ocular pressure (IOP). When used with other herbs or supplements that decrease IOP, it may result in additive effects.

Colenol, a compound isolated from coleus, stimulates insulin release, and its use with blood sugar lowering herbs or supplements, such as bitter melon, may result in additive effects.

               
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