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  • Basic Info
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Generic: clozapine
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It is used to treat schizophrenia
               



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What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • cisapride
  • dofetilide
  • dronedarone
  • fluconazole
  • medicines for treating cancer
  • medicines that lower your chance of fighting infection
  • mesoridazine
  • metoclopramide
  • pimozide
  • posaconazole
  • quinidine
  • thioridazine
  • ziprasidone

This medicine may also interact with the following medications:

  • alcohol
  • antihistamines for allergy, cough and cold
  • atropine
  • birth control pills
  • caffeine
  • certain antibiotics like ciprofloxacin, erythromycin, mefloquine, moxifloxacin
  • certain medicines for bladder problems like oxybutynin, tolterodine
  • certain medicines for depression, anxiety, or psychotic disturbances
  • certain medicines for irregular heart beat like amiodarone, encainide, flecainide, propafenone, sotalol
  • certain medicines for Parkinson's disease like benztropine, trihexyphenidyl
  • certain medicines for sleep
  • certain medicines for stomach problems like dicyclomine, hyoscyamine
  • certain medicines for travel sickness like scopolamine
  • cimetidine
  • dolasetron
  • enoxacin
  • ipratropium
  • lithium
  • medicines for blood pressure
  • medicines for seizures
  • methadone
  • nicotine
  • pentamidine
  • rifampin or rifabutin
  • skeletal muscle relaxants
  • St. John's Wort
  • tacrolimus
  • terbinafine

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress. It may be several weeks before you see the full effects of this medicine. Contact your doctor or health care professional if your symptoms get worse or if you have new symptoms.

You must have a weekly blood test when you first begin this medicine. If your blood counts stay in the right range, your tests may be reduced after 6 months to every other week. Your name will go on a national registry of patients that take this medicine, to make sure that you have never had a serious reaction to it.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this drug affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can make you more drowsy and dizzy. Avoid alcoholic drinks.

Do not treat yourself for colds, fever, diarrhea or allergies. Ask your doctor or health care professional for advice, some nonprescription medicines may increase possible side effects.

If you are going to have surgery tell your doctor or health care professional that you are taking this medicine.

This medicine can reduce the response of your body to heat or cold. Dress warm in cold weather and stay hydrated in hot weather. If possible, avoid extreme temperatures like saunas, hot tubs, very hot or cold showers, or activities that can cause dehydration such as vigorous exercise.

               
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