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  • Basic Info
Licensed from
Generic: Catha edulis
treats Cognitive function

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DISCLAIMER: Natural Standard developed the above evidence- based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.

Adeoya- Osiguwa SA, Fraser LR. Cathine and norephedrine, both phenylpropanolamines, accelerate capacitation and then inhibit spontaneous acrosome loss. Hum.Reprod. 2005;20(1):198- 207.

Al Motarreb AL Broadley KJ. Coronary and aortic vasoconstriction by cathinone, the active constituent of khat. Auton.Autacoid.Pharmacol 2003;23(5- 6):319- 326.

Al Motarreb A, Briancon S, Al Jaber N, et al. Khat chewing is a risk factor for acute myocardial infarction: a case- control study. Br J Clin Pharmacol 2005;59(5):574- 581.

Al Zubairi A, Al Habori M, Al Geiry A. Effect of Catha edulis (khat) chewing on plasma lipid peroxidation. J.Ethnopharmacol. 2003;87(1):3- 9.

Belhadj- Tahar H, Sadeg N. Methcathinone: a new postindustrial drug. Forensic Sci Int 10- 4- 2005;153(1):99- 101.

Dimba EA, Gjertsen BT, Bredholt T, et al. Khat (Catha edulis)- induced apoptosis is inhibited by antagonists of caspase- 1 and - 8 in human leukaemia cells. Br.J.Cancer 11- 1- 2004;91(9):1726- 1734.

Hassan NA, Gunaid AA, El Khally FM, et al. Khat chewing and arterial blood pressure. A randomized controlled clinical trial of alpha- 1 and selective beta- 1 adrenoceptor blockade. Saudi.Med J 2005;26(4):537- 541.

Hassan NA, Gunaid AA, El Khally FM, et al. The effect of chewing Khat leaves on human mood. Saudi.Med.J. 2002;23(7):850- 853.

Kassim S, Croucher R. Khat chewing amongst UK resident male Yemeni adults: an exploratory study. Int Dent.J 2006;56(2):97- 101.

Kuczkowski KM. Herbal ecstasy: cardiovascular complications of khat chewing in pregnancy. Acta Anaesthesiol.Belg. 2005;56(1):19- 21.

Murugan N, Burkhill G, Williams SG, et al. The effect of khat chewing on gallbladder motility in a group of volunteers. J.Ethnopharmacol. 2003;86(2- 3):225- 227.

Nasher AA, Qirbi AA, Ghafoor MA, et al. Khat chewing and bladder neck dysfunction. A randomized controlled trial of alpha 1- adrenergic blockade. Br.J.Urol. 1995;75(5):597- 598.

Patel NB. Mechanism of action of cathinone: the active ingredient of khat (Catha edulis). East Afr.Med.J. 2000;77(6):329- 332.

Toennes SW, Kauert GF. Driving under the influence of khat- - alkaloid concentrations and observations in forensic cases. Forensic Sci.Int. 2- 10- 2004;140(1):85- 90.

Toennes SW, Harder S, Schramm M, et al. Pharmacokinetics of cathinone, cathine and norephedrine after the chewing of khat leaves. Br.J.Clin.Pharmacol. 2003;56(1):125- 130.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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