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  • Basic Info
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What is this medicine?

CAPTOPRIL; HYDROCHLOROTHIAZIDE (KAP toe pril; hye droe klor oh THYE a zide) is a combination of a diuretic and an ACE inhibitor. It is used to treat high blood pressure.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • bone marrow disease
  • decreased urine
  • heart or blood vessel disease
  • if you are on a special diet like a low salt diet
  • immune system problems, like lupus
  • kidney disease
  • liver disease
  • previous swelling of the tongue, face, or lips with difficulty breathing, difficulty swallowing, hoarseness, or tightening of the throat
  • recent heart attack or stroke
  • an unusual or allergic reaction to captopril, hydrochlorothiazide, sulfa drugs, other medicines, insect venom, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast- feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take this medicine on an empty stomach, at least 1 hour before meals. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking this medicine except on the advice of your doctor or health care professional.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

  • amphotericin b
  • barbiturates like phenobarbital
  • blood pressure medicines
  • calcium supplements
  • corticosteroids like prednisone
  • diabetic medications
  • digoxin
  • diuretics, especially potassium- sparing diuretics like triamterene, spironolactone or amiloride
  • lithium
  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
  • medicines for angina like nitroglycerin
  • medicines that treat or prevent blood clots like warfarin
  • medicines used to treat gout
  • methenamine
  • NSAIDs like ibuprofen
  • potassium salts or potassium supplements
  • prescription pain medicines
  • skeletal muscle relaxants like tubocurarine
  • some cholesterol- lowering medications like cholestyramine or colestipol

               
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