Interactions

Interactions with Drugs

Although not well studied in humans, boneset may have weak antibacterial and anti- inflammatory effects. Caution is advised in patients taking agents that have similar effects.

Homeopathic boneset may have antiviral effects. Caution is advised in patients taking other antiviral agents or immunomodulators.

Boneset may cause excessive fluid loss from the body, possibly also decreasing the body's potassium supplies. Low potassium levels can result in muscle weakness and potentially dangerous changes in heart rhythm.

Unsaturated pyrrolizidine alkaloids are common in the genus of boneset and might be in boneset as well. Caution is advised when taking agents that are potentially liver damaging, as the combination may increase the risk of liver damage.

Interactions with Herbs and Dietary Supplements

Although not well studied in humans, boneset may have weak antibacterial and anti- inflammatory effects. Caution is advised in patients taking herbs or supplements that have similar effects.

Homeopathic boneset may have antiviral effects. Caution is advised in patients taking other antiviral agents or immunomodulators.

Boneset may cause excessive fluid loss from the body, possibly also decreasing the body's potassium supplies. Low potassium levels can result in muscle weakness and potentially dangerous changes in heart rhythm. Caution is advised in patients taking potassium or any herbs or supplements with diuretic effects.

Unsaturated pyrrolizidine alkaloids are common in the genus of boneset and might be in boneset as well. Caution is advised when taking herbs or supplements that are potentially liver damaging, as the combination may increase the risk of liver damage.

Attribution

This information is based on a systematic review of scientific literature, and was peer- reviewed and edited by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com): Ashley Brigham, PharmD (Northeastern University); Dawn Costa, BA, BS (Natural Standard Research Collaboration); Thuy- Duong Le, PharmD (Oregon State University); Nicole Giese, MS (Natural Standard Research Collaboration); Shaina Tanguay- Colucci, BS (Natural Standard Research Collaboration); Catherine Ulbricht, PharmD (Massachusetts General Hospital); Wendy Weissner, BA (Natural Standard Research Collaboration).