Generic: Bellis perennis
Interactions with Drugs
Bellis perennis may affect coagulation and it is unclear how this herb may interact with medications that may increase the risk of bleeding. Examples include aspirin, anticoagulants ("blood thinners") such as warfarin (Coumadin®) or heparin, anti- platelet drugs such as clopidogrel (Plavix®), and non- steroidal anti- inflammatory drugs (NSAIDS) such as ibuprofen (Motrin®, Advil®) or naproxen (Naprosyn®, Aleve®). Caution is advised.
Interactions with Herbs and Dietary Supplements
Bellis perennis may affect coagulation, and it is unclear how this herb may interact with herbs and supplements that may increase the risk of bleeding. Caution is advised when taking with herbs and supplements that may increase the risk of bleeding, such as garlic or Ginkgo biloba.
This patient information is based on a systematic review of scientific literature edited and peer- reviewed by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com): J. Kathryn Bryan, BA (Natural Standard Research Collaboration); Jessica Clubb, PharmD (Northeastern University); Molly Davis, PharmD (University of Rhode Island); Antoinette Edmondson, PharmD (Massachusetts College of Pharmacy); Nicole Giese, MS (Natural Standard Research Collaboration); Petra Jancar, PharmD (University of Ljubljana); Toni M. Schaeffer, PhD, PharmD (Albany College of Pharmacy); Shaina Tanguay- Colucci, BS (Natural Standard Research Collaboration); Wendy Weissner, BA (Natural Standard Research Collaboration).
BibliographyDISCLAIMER: Natural Standard developed the above evidence- based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.
Avato P, Vitali C, Mongelli P, et al. Antimicrobial activity of polyacetylenes from Bellis perennis and their synthetic derivatives. Planta Med 1997;63(6):503- 507.
Bader G, Kulhanek Y, Ziegler- Bohme H. [The antifungal action of polygalacic acid glycosides]. Pharmazie 1990;45(8):618- 620.
Desevedavy C, Amoros M, Girre L, et al. Antifungal agents: in vitro and in vivo antifungal extract from the common daisy, Bellis perennis. J Nat.Prod. 1989;52(1):184- 185.
Glensk M, Wray V, Nimtz M, et al. Triterpenoid saponins of Bellis perennis. Scientia Pharmaceutica 2001;69- 73.
Gudej J, Nazaruk J. Flavonol glycosides from the flowers of Bellis perennis. Fitoterapia 2001;72(7):839- 840.
Guneser S, Atici A, Cengizler I, et al. Inhalant allergens: as a cause of respiratory allergy in east Mediterranean area, Turkey. Allergol.Immunopathol.(Madr.) 1996;24(3):116- 119.
Nazaruk J, Gudej J. Apigenin glycosides from the flowers of Bellis perennis L. Acta Pol.Pharm 2000;57(2):129- 130.
Nazaruk J, Gudej J. Qualitative and quantitative chromatographic investigation of flavonoids in Bellis perennis L. Acta Pol.Pharm 2001;58(5):401- 404.
Oberbaum M, Galoyan N, Lerner- Geva L, et al. The effect of the homeopathic remedies Arnica montana and Bellis perennis on mild postpartum bleeding- - a randomized, double- blind, placebo- controlled study- - preliminary results. Complement Ther.Med 2005;13(2):87- 90.
Schopke T, Hiller K, Wray V, et al. Triterpenoid saponins from Bellis sylvestris, I. Structures of the major deacylsaponins. J Nat.Prod. 1994;57(9):1279- 1282.
Schopke T, Wray V, Kunath A, et al. Bayogenin and asterogenic acid glycosides from Bellis perennis. Phytochemistry 1992;31(7):2555- 2557.
Schopke T, Wray V, Kunath A, et al. Virgaureasaponin 2 from Bellis perennis L. Die Pharmazie 1- 1- 1990;45:870- 871.
Siatka T, Kasparova M. [Seasonal changes in the hemolytic effects of the head of Bellis perennis L.]. Ceska.Slov.Farm 2003;52(1):39- 41.
Siatka T, Kasparova M, Dusek J. Seasonal variation in haemolytic activity of Bellis perennis L. leaves and roots. Folia Pharmaceutica Universitatis Carolinae 2002;85- 89.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.