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  • Basic Info
Licensed from
Generic: Globe artichoke
treats Alcohol-induced hangover, Antioxidant, Dyspepsia, Irritable bowel syndrome, Choleretic, and Lipid-lowering
               



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Interactions

Interactions with Drugs

Artichoke may increase the risk of bleeding when taken with drugs that increase the risk of bleeding. Some examples include aspirin, anticoagulants ("blood thinners") such as warfarin (Coumadin®) or heparin, anti- platelet drugs such as clopidogrel (Plavix®), and non- steroidal anti- inflammatory drugs (NSAIDS) such as ibuprofen (Motrin®, Advil®) or naproxen (Naprosyn®, Aleve®).

There are multiple published reports of cholesterol- lowering effects of artichoke, although the quality of most studies is not sufficient to form a clear conclusion in this area. Artichoke may add to the cholesterol- lowering effects of other agents.

Interactions with Herbs & Dietary Supplements

Artichoke may increase the risk of bleeding when taken with herbs and supplements that are believed to increase the risk of bleeding. Multiple cases of bleeding have been reported with the use of Ginkgo biloba, and fewer cases with garlic and saw palmetto. Numerous other agents may theoretically increase the risk of bleeding, although this has not been proven in most cases.

There are multiple published reports of cholesterol- lowering effects of artichoke, although the quality of most studies is not sufficient to form a clear conclusion in this area. Therefore, artichoke may add to the lipid- lowering effects of other agents, such as fish oil, garlic, or niacin.

Attribution

This information is based on a systematic review of scientific literature, and was peer- reviewed and edited by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com): Ethan Basch, MD (Memorial Sloan- Kettering Cancer Center); Heather Boon, B.Sc.Phm, PhD (University of Toronto); Ashley Brigham, PharmD (Northeastern University); Joan Engebretson, DrPH, RN (University of Texas); Nicole Giese, MS (Natural Standard Research Collaboration); Ernest B. Hawkins, MS, BSPharm (Health Education Resources, Inc.); Charles Holmes, MD (Harvard Medical School); Michael Smith, M.R.PharmS, ND (Canadian College of Naturopathic Medicine); Shaina Tanguay- Colucci, BS (Natural Standard Research Collaboration); Catherine Ulbricht, PharmD (Massachusetts General Hospital); Wendy Weissner, BA (Natural Standard Research Collaboration); Heeja Yoon, PharmD (Drake University).

               
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