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  • Basic Info
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Generic: Globe artichoke
treats Alcohol-induced hangover, Antioxidant, Dyspepsia, Irritable bowel syndrome, Choleretic, and Lipid-lowering

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DISCLAIMER: Many complementary techniques are practiced by healthcare professionals with formal training, in accordance with the standards of national organizations. However, this is not universally the case, and adverse effects are possible. Due to limited research, in some cases only limited safety information is available.


Avoid in individuals with a known allergy or hypersensitivity to globe artichoke (Cynara scolymus L.), its constituents, or members of the Asteraceae or Compositae family, including chrysanthemums, daisies, marigolds, ragweed, and arnica, due to possible cross- reactivity. Symptoms of allergy may include worsening of asthma, skin rash, anaphylactic shock, dyspnea (difficulty breathing), cough, and chest tightness. While rare, individuals with a known inulin allergy should avoid artichokes and artichoke extracts.

Side Effects and Warnings

Artichoke is likely safe when taken by mouth for short periods of time. The adverse effects associated with artichoke are generally mild and include gastrointestinal symptoms. However, there have been reports of kidney failure and/ or toxicity from the use of artichoke leaves. Use cautiously in patients with kidney disease.

Contact dermatitis (rash) and contact urticaria have been noted after application to the skin, with symptoms spontaneously subsiding hours or days after exposure.

Mild flatulence (gas), diarrhea, hunger, redness in the face, increased bile secretion, and nausea have been reported. Use cautiously in patients with cholelithiasis (gallstones) or biliary/ bile duct obstruction.

Artichoke extract (Cynarex®) may increase the risk of bleeding, although causality is unclear. Caution is advised in patients with bleeding disorders or taking drugs that may increase the risk of bleeding. Dosing adjustments may be necessary.

Dyspnea (difficulty breathing), cough, chest tightness, and a severe asthma exacerbation may occur. Severe anaphylactic shock in response to artichoke inulin as an ingredient in commercially available products has also been reported. Individuals with a noted sensitivity to artichokes should consume inulin with caution. While rare, individuals with a known inulin allergy should avoid artichokes and artichoke extracts.

Pregnancy & Breastfeeding

Artichoke is not recommended in pregnant or breastfeeding women due to a lack of available sufficient evidence.

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