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Generic: Apricot
               



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Interactions

Interactions with Drugs

Apricot kernels may cause decreases in blood pressure, and therefore may interact with blood pressure lowering medications. A qualified healthcare professional, including a pharmacist, should be consulted.

Interactions with Herbs and Dietary Supplements

Apricot kernels may cause decreases in blood pressure, and therefore may interact with blood pressure lowering herbs and supplements. A qualified healthcare professional, including a pharmacist, should be consulted.

Apricot contains beta- carotene, iron, niacin, potassium, thiamine and vitamin C. Taking apricot with these supplements may have additive effects. Caution is advised.

Laetrile™ and apricot kernels both contain amygdalin, and concomitant use may result in cyanide poisoning. Caution is advised.

Attribution

This information is based on a professional level monograph edited and peer- reviewed by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com): Deena Beneda- Khosh, ND (University of Kansas Medical Center); Rebecca Bramwell, PharmD (Northeastern University); Huong Thien Dang, PharmD (Massachusetts College of Pharmacy); Nicole Giese, MS (Natural Standard Research Collaboration); Erica Rusie, PharmD (Nova Southeastern University); Shaina Tanguay- Colucci, BS (Natural Standard Research Collaboration); William Tobin (Natural Standard Research Collaboration); Catherine Ulbricht, PharmD (Massachusetts General Hospital); Wendy Weissner, BA (Natural Standard Research Collaboration); Jen Woods, BS (Northeastern University).

Bibliography

DISCLAIMER: Natural Standard developed the above evidence- based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.

Araya E, Rodriguez A, Rubio J, et al. Synthesis and evaluation of diverse analogs of amygdalin as potential peptidomimetics of peptide T. Bioorg.Med Chem Lett. 3- 1- 2005;15(5):1493- 1496.

Bhatti RA, Ablin RJ, Guinan PD. Tumour- associated directed immunity in prostatic cancer: effect of amygdalin. IRCS Med Sci 1981;9(1):19.

Hill GJ, Shine TE, Hill HZ, et al. Failure of amygdalin to arrest B16 melanoma and BW5147 AKR leukemia. Cancer Res 1976;36(6):2102- 2107.

Laster WR Jr, Schabel FM Jr. Experimental studies of the antitumor activity of amygdalin MF (NSC- 15780) alone and in combination with beta- glucosidase (NSC- 128056). Cancer Chemother Rep 1975;59(5):951- 965.

Lea MA, Koch MR. Effects of cyanate, thiocyanate, and amygdalin on metabolite uptake in normal and neoplastic tissues of the rat. J Natl.Cancer Inst. 1979;63(5):1279- 1283.

Moertel CG, Fleming TR, Rubin J, et al. A clinical trial of amygdalin (Laetrile) in the treatment of human cancer. N.Engl.J.Med. 1- 28- 1982;306(4):201- 206.

Morrone JA. Chemotherapy of inoperable cancer: preliminary report of 10 cases treated with laetrile. J Exper Med Surg 1962;20:299- 308.

Moss RW. Patient perspectives: Tijuana cancer clinics in the post- NAFTA era. Integr.Cancer Ther 2005;4(1):65- 86.

Navarro MD. The Philippine experience in the early detection and chemotherapy of cancer. Santo Tomas J Med 1970;25(3):125- 133.

Ovejera AA, Houchens DP, Barker AD, et al. Inactivity of DL- amygdalin against human breast and colon tumor xenografts in athymic (nude) mice. Cancer Treat.Rep 1978;62(4):576- 578.

Ross WE. Unconventional cancer therapy. Compr.Ther 1985;11(9):37- 43.

Smith FP, Butler TP, Cohan S, et al. Laetrile toxicity: a report of two patients. Cancer Treat.Rep 1978;62(1):169- 171.

Syrigos KN, Rowlinson- Busza G, Epenetos AA. In vitro cytotoxicity following specific activation of amygdalin by beta- glucosidase conjugated to a bladder cancer- associated monoclonal antibody. Int J Cancer 12- 9- 1998;78(6):712- 719.

Vickers A. Alternative cancer cures: "unproven" or "disproven"? CA Cancer J Clin 2004;54(2):110- 118.

Wodinsky I, Swiniarski JK. Antitumor activity of amygdalin MF (NSC- 15780) as a single agent and with beta- glucosidase (NSC- 128056) on a spectrum of transplantable rodent tumors. Cancer Chemother Rep 1975;59(5):939- 950.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

               
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