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  • Basic Info
Licensed from
Generic: Alfalfa
treats Atherosclerosis, High cholesterol, and Diabetes
               



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Attribution

This information is based on a professional level monograph edited and peer- reviewed by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com): Ethan Basch, MD (Memorial Sloan- Kettering Cancer Center); Dawn Costa, BA, BS (Natural Standard Research Collaboration); Cathi Dennehy, PharmD (University of California, San Francisco); Nicole Giese, MS (Natural Standard Research Collaboration); Mary Giles, PharmD (University of Rhode Island); Michael Goble, BS, PharmD (Massachusetts College of Pharmacy); Michelle Harrison, PharmD (New England Medical Center); David Kroll, PhD (Duke University); Richard Liebowitz, MD (Duke University); Erica Seamon, PharmD (Natural Standard Research Collaboration); Michael Smith, MRPharmS, ND (Canadian College of Naturopathic Medicine); David Sollars, MAc, HMC (New England School of Acupuncture); Philippe Szapary, MD (University of Pennsylvania); Shaina Tanguay- Colucci, BS (Natural Standard Research Collaboration); Catherine Ulbricht, PharmD (Massachusetts General Hospital); Mamta Vora, PharmD (Northeastern University); Wendy Weissner, BA (Natural Standard Research Collaboration); Jen Woods, BS (Natural Standard Research Collaboration).

Bibliography

DISCLAIMER: Natural Standard developed the above evidence- based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.

Anon. From the Centers for Disease Control and Prevention. Outbreaks of Escherichia coli O157:H7 infection associated with eating alfalfa sprouts- - Michigan and Virginia, June- July 1997. JAMA 9- 10- 1997;278(10):809- 810.

Bengtsson AA, Rylander L, Hagmar L, et al. Risk factors for developing systemic lupus erythematosus: a case- control study in southern Sweden. Rheumatology (Oxford) 2002;41(5):563- 571.

Boue SM, Wiese TE, Nehls S, et al. Evaluation of the estrogenic effects of legume extracts containing phytoestrogens. J Agric Food Chem 4- 9- 2003;51(8):2193- 2199.

Burden and causes of foodborne disease in Australia: Annual report of the OzFoodNet network, 2005. Commun Dis Intell 2006;30(3):278- 300.

Farnsworth NR. Alfalfa pills and autoimmune diseases. Am J Clin Nutr 1995;62(5):1026- 1028.

Hwang J, Hodis HN, Sevanian A. Soy and alfalfa phytoestrogen extracts become potent low- density lipoprotein antioxidants in the presence of acerola cherry extract. J Agric Food Chem 2001;49(1):308- 314.

Lanza A, Tava A, Catalano M, et al. Effects of the Medicago scutellata trypsin inhibitor (MsTI) on cisplatin- induced cytotoxicity in human breast and cervical cancer cells. Anticancer Res 2004;24(1):227- 233.

Malinow MR, McLaughlin P, Naito HK, et al. Regression of atherosclerosis during cholesterol feeding in Macaca fascicularis. Am J Cardiol 1978;41:396.

Malinow MR, McLaughlin P, Naito HK, et al. Effect of alfalfa meal on shrinkage (regression) of atherosclerotic plaques during cholesterol feeding in monkeys. Atherosclerosis 1978;30(1):27- 43.

Malinow MR, McLaughlin P, Stafford C. Alfalfa seeds: effects on cholesterol metabolism. Experientia 5- 15- 1980;36(5):562- 564.

Malinow MR, Bardana EJ Jr, Goodnight SH Jr. Pancytopenia during ingestion of alfalfa seeds. Lancet 3- 14- 1981;1(8220 Pt 1):615.

Molgaard J, von Schenck H, Olsson AG. Alfalfa seeds lower low density lipoprotein cholesterol and apolipoprotein B concentrations in patients with type II hyperlipoproteinemia. Atherosclerosis 1987;65(1- 2):173- 179.

Srinivasan SR, Patton D, Radhakrishnamurthy B, et al. Lipid changes in atherosclerotic aortas of Macaca fascicularis after various regression regimens. Atherosclerosis 1980;37(4):591- 601.

Swanston- Flatt SK, Day C, Bailey CJ, et al. Traditional plant treatments for diabetes. Studies in normal and streptozotocin diabetic mice. Diabetologia 1990;33(8):462- 464.

Van Beneden CA, Keene WE, Strang RA, et al. Multinational outbreak of Salmonella enterica serotype Newport infections due to contaminated alfalfa sprouts. JAMA 1- 13- 1999;281(2):158- 162.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

               
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