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  • Basic Info
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Generic: apap/caffeine/mg salicylate/phenyltoloxamine
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It is used to relieve mild to moderate pain from headaches, the common cold, flu, or a sinus infection

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What is this medicine?

ACETAMINOPHEN; CAFFEINE; MAGNESIUM SALICYLATE; PHENYLTOLOXAMINE (a set a MEE noe fen; KAF een; mag NEE zhum sa LIS i late; fen ill toe LOX a meen) is a pain reliever. It is used to relieve mild to moderate pain from headaches, the common cold, flu, or a sinus infection. It may also be used for pain from menstrual cramps, muscle or nerve pain, and arthritis.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • asthma
  • blood clotting problems
  • glaucoma
  • heart disease
  • high blood pressure
  • if you frequently drink alcohol containing drinks
  • kidney disease
  • liver disease
  • prostate problems
  • stomach ulcer or other problem
  • trouble passing urine
  • an unusual reaction to acetaminophen, caffeine, magnesium salicylate, phenyltoloxamine, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast- feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take your medicine at regular intervals. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Patients over 65 years old may have a stronger reaction and need a smaller dose.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
  • methotrexate

This medicine may also interact with the following medications:

  • acetaminophen
  • acetazolamide
  • alcohol
  • antibiotics like ciprofloxacin, gatifloxacin, tetracycline
  • antihistamines for allergies or cold
  • aspirin and aspirin- like drugs
  • caffeine
  • green tea
  • lithium
  • medicines for asthma or other breathing problems
  • medicines for depression, anxiety, or psychotic disturbances
  • medicines for sleep
  • muscle relaxants
  • phenobarbital
  • phenytoin, and fosphenytoin
  • varicella live vaccine
  • warfarin

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