Exciting news on experimental treatments! A new study on Type 1 diabetics showed that injecting the antibody anti-CD3 may help "stop this autoimmune disease in its tracks," according to JDRF executive VP for research Dr. Richard Insel.

Researchers at Necker Hospital in Paris apparently tested this "novel approach" on newly diagnosed Type 1 diabetics who still had some insulin function left. The results, published last week in the New England Journal of Medicine, were encouraging enough for the JDRF to plan future large-scale studies.

DiabetesdrugWhat they did this time was randomly divide 80 patients recently

diagnosed with Type 1 diabetes into two groups -- one getting the antibody treatment intravenously and the other getting a

placebo. The researchers recorded insulin doses and evaluated

how well the patients' pancreatic cells produced insulin at the

beginning of the study and also at six, 12, and 18 months following treatment.

What they found out was that within the 18 months, the placebo patients needed more insulin and had a decrease in the functioning of their insulin-producing cells, whereas the anti-body receivers had little change at all in their insulin needs or islet cell function. In other words, it looks like the drug may stop the attack on pancreatic cells!

BUT: there are safety concerns. Most who got the treatment had side effects including headaches, fever, joint aches, and rashes. These are supposedly temporary, but could increase risk of a blood disorder down the line.

AND: "Since the trial lasted for only 18 months, it is unclear if the treatment could 'wear off' after a certain period of time."

Yes, we know: Don't get too excited. But a fascinating development, nonetheless.

Disclaimer: Content created by the Diabetes Mine team. For more details click here.


This content is created for Diabetes Mine, a consumer health blog focused on the diabetes community. The content is not medically reviewed and doesn't adhere to Healthline's editorial guidelines. For more information about Healthline's partnership with Diabetes Mine, please click here.