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Causes could include:
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Gene Mutation
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However, most cases are due to new mutations, so there usually is no family history of tuberous sclerosis.This condition is one of a group of diseases called neuro-cutaneous syndromes. Both the skin and central nervous system(brain and spinal cord...
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TSC is an autosomal dominant genetic disorder caused by a single change or alteration in a gene called a mutation in either the TSC1 gene, located on chromosome 9, or the TSC2 gene, located on chromosome 16. Approximately two-thirds (66%) of pati...
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Always known to be hereditary, mutations in two different genes are now known to cause TS. These genes are TSC1 and TSC2, and were discovered in 1993 and 1997 on chromosomes 16 and 9 respectively.
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TSC is an autosomal dominant genetic disorder caused by a single change or alteration in a gene called a mutation in either the TSC1 gene, located on chromosome 9, or the TSC2 gene, located on chromosome 16. Approximately two-thirds (66%) of pati...
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Tuberous sclerosis occurs when at least one of two genes (either TSC-1 on chromosome 9 or TSC-2 on chromosome 16) is defective. Normally, the two genes produce proteins called hamartin and tuberin, respectively.
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In a strict sense, mutations are changes in genes not caused by genetic recombination. A change in the base sequence of DNA, for example, represents a mutational change.
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