Sign up with Facebook
- Health A to Z
- Healthy Living
Advertisement
Tuberous Sclerosis Learning Center
Causes could include:
-
Gene Mutation
 |
Tuberous sclerosis is inherited. Changes (mutations) in two genes, TSC1 and TSC2, are responsible for the condition.
|
|
TSC is an autosomal dominant genetic disorder caused by a single change or alteration in a gene called a mutation in either the TSC1 gene, located on chromosome 9, or the TSC2 gene, located on chromosome 16. Approximately two-thirds (66%) of patie...
|
|
Always known to be hereditary, mutations in two different genes are now known to cause TS. These genes are TSC1 and TSC2, and were discovered in 1993 and 1997 on chromosomes 16 and 9 respectively. TS is inherited in an autosomal dominant manner, m...
|
|
TSC is an autosomal dominant genetic disorder caused by a single change or alteration in a gene called a mutation in either the TSC1 gene, located on chromosome 9, or the TSC2 gene, located on chromosome 16. Approximately two-thirds (66%) of patie...
|
|
Tuberous sclerosis occurs when at least one of two genes (either TSC-1 on chromosome 9 or TSC-2 on chromosome 16) is defective. Normally, the two genes produce proteins called hamartin and tuberin, respectively. These proteins seem to serve as inh...
|
|
In a strict sense, mutations are changes in genes not caused by genetic recombination. A change in the base sequence of DNA , for example, represents a mutational change. Spontaneous mutations are mutations that occur at a given frequency without ...
|
