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Thrombotic Thrombocytopenic Purpura (TTP) Learning Center
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Basic Info
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Thrombotic Thrombocytopenic Purpura (TTP)
TTP is a blood disorder characterized by low platelets , low red blood cell count (caused by premature breakdown of the cells), abnormalities in kidney function, and neurological (nervous system) abnormalities. A simila...
Basic Info
Symptoms
Fever; Weakness; Easy fatigue; Pallor; Shortness of breath on exertion; Heart rate over 100 beats per minute; Purplish ...
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Causes
In some cases, this disease is caused by the lack of an enzyme (a type of protein) that is involved in blood clotting. ...
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Tests
Platelet count is low; CBC shows anemia; Bilirubin is high; Blood smear shows broken red blood cells (schistocytes) and...
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Treatments
Plasma exchange (plasmapheresis) is used to remove unwanted substances from the blood and to replace the missing enzyme...
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Drugs
cycloSPORINE
rituximab
vinCRIStine
more
Risk Factors
Chemotherapy
clopidogrel
cycloSPORINE
more
Complications
Kidney failure; Severe bleeding (hemorrhage; Stroke.
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Prevention
Because the specific cause is unknown, there is no known way to prevent this condition.
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Doctor Specialties
Call your health care provider if you have any unexplained bleeding.
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