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Systemic Lupus Erythematosus Learning Center
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Systemic lupus erythematosus is an autoimmune connective-tissue disorder with a wide range of clinical features, which predominantly affects women, especially from certain ethnic groups. Diagnosis is based on clinical assessment supported by investigations, including the finding of autoantibodies.
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The following Clinical Topic Tour provides an overview of systemic lupus erythematosus (SLE) and was adapted from materials published by the National Institute of Arthritis and Musculoskeletal and Skin Diseases.
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Systemic lupus erythematosus (SLE) is a diverse autoimmune rheumatic disease principally affecting women during childbearing years. The female-to-male ratio is around 9:1.
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Management of systemic lupus erythematosus (SLE) is a challenge because no interventions can result in cure, exacerbations of disease can occur after months of stable maintenance treatment, and undesirable side effects of the therapies can be as troublesome as the disease. Careful and frequent monitoring of patients is important in selecting management plans, monitoring efficacy, and changing treatments.
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