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Pregnancy : Health Experts

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The other day, tjtiger left a new comment on my post"MTHFR Mutations and Congenital Heart Defects". Her many questions made her comment worthy of a post of their own and the query related to the possible assocation of MTHFR polymorhisms and schizo...
Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:October 3, 2007
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Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:September 17, 2007
I had 2 miscarriages in 6 months(7 wks, and 8 weeks with 2 normal periods in between). I was told I was heterozygous C677T MTHFR...no elevated homocysteine level which I didn't test after fasting...doctor did not seem too concerned about preparing...
Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:September 7, 2007
Soumya has left a new comment on your post" Recurrent Early Pregnancy Loss- 6- A Special Pat...". (I have modified/revised her comment somewhat to the best of my understanding of her concerns)...
Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:August 17, 2007
Well, the flu season is underway, and every pregnant woman wants to know, Should I get the flu shot?. The simple answer is YES(with few exceptions), no matter how early or far along you are in your pregnancy, and the optimal time to receive the va...
Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:October 15, 2006
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Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:February 7, 2007
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Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:December 18, 2007
The readers who sent in the comments below related to recurrent early pregnancy loss(RPL) have what we could consider to be'borderline' indications for'treatment' and several questions related to their therapy. But, the fact remains, they have bot...
Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:December 9, 2007
In our last post, we reviewed several studies that would lend support to the hypothesis that women with elevated levels of plasminogen activator inhibitor-1(PAI-1), and a genetic predisposition for the same, are at increased risk for adverse pregn...
Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:November 5, 2007
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Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:June 10, 2008
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Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:December 22, 2007
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Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:September 11, 2007
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Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:April 12, 2007
Before I get into details regarding specific abnormalities of the maternal immune system and clotting system that appear to be related to recurrent early pregnancy loss, let me tell you a story about one of those special patients in my life who ch...
Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:April 3, 2007
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Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:March 24, 2007
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Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:March 16, 2007
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Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:March 15, 2007
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Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:January 10, 2007
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Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:July 11, 2009
Back in June, a reader I.R. left a comment on my post"Recurrent Early Pregnancy Loss- 7- Immunologic a...". Her specific question related to the possible role of plasminogen activator inhibitor 1(PAI 1) activity and polymorphisms in recurrent preg...
Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:September 30, 2007
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Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:November 20, 2007
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Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:August 31, 2009
For many years now, we have placed women with recurrent early pregnancy loss on low-dose aspirin(81 mg) and heparin, or low molecular-weight heparin such as lovenox, to help them improve their prospects for pregnancy outcome. In some instances thi...
Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:January 26, 2008
The last two major categories I would like to discuss related to recurrent early pregnancy loss are immunologic and hematological(thrombophilias) abnormalities. These may well be the most common causes, but they are also by far the least well unde...
Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:April 1, 2007
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Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:March 8, 2008
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Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:August 29, 2007
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Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:January 13, 2007
For example, if 1 in 30 pregnancies is twins then about 1 in 1100 would be triplets, and 4 in 100,000 would be quadruplets. Actual findings of higher order multiples in the population support these predicted distributions.
Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:January 2, 2009
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Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:December 15, 2007
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Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:February 9, 2009
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Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:July 5, 2009
Since constipation can be a chronic and ongoing concern in pregnancy, it is worth revisiting at least once with a few additional comments. Actually, the writer referred to in the previous post had some more specific follow-up questions and my resp...
Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:March 10, 2007
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Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:May 1, 2008
Today is the start of my 34th week of pregnancy!. I am starting to get ready, nesting a little bit, and also dealing with some anxiety!.
Author:Tara Gidus, MS, RD, CSSD, LD/N
Date:May 9, 2007
In our fifth post in this series, we discussed a case of a woman who had a high-grade intraepithelial abnormality(HSIL) found on her intake Pap test and was subsequently diagnosed with minimally invasive cervical cancer(stage 1A1) during her pregn...
Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:July 22, 2007
A writer recently requested some information regarding"constipation in pregnancy.". Having just gotten over the consequences of my Norovirus infection, I thought I might welcome a little constipation in my life, even if it isn't one of our more'mo...
Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:March 6, 2007
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Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:October 13, 2007
In our last post, we discussed the basic differences between type 1 and type 2 diabetes and concluded with the characterization of gestational diabetes mellitus(GDM), diabetes that is first expressed(or detected) as the result of pregnancy, as fit...
Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:December 29, 2007
Now that you know not to eat double portions of everything and you have learned to love your body, lets finish this series with some other helpful hints for what to eat and not eat when you are pregnant.
Author:Tara Gidus, MS, RD, CSSD, LD/N
Date:May 14, 2007
Yesterday I talked about how much to eat, what to eat, and the importance of supplements in Pregnancy Do's and Donts Part One. Today I will go in a different direction with what I have learned during pregnancy.
Author:Tara Gidus, MS, RD, CSSD, LD/N
Date:May 11, 2007
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Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:May 16, 2008
In a recent post we discussed"A Complication of Methotrexate Use for Ectopic Pregnancy..." and in response to that post we had several excellent questions from our readers. The queries below should be of general interest to many women who undergo ...
Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:October 15, 2007
The"back ache" could also be uterine contractions associated with miscarriage or caused by something outside the uterus such as an ectopic pregnancy or ovarian cyst. At 7 weeks, your doctor can do a transvaginal ultrasound and should be able to co...
Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:August 12, 2007
Our last post detailed the management of a pregnant woman who was found to have multifocal carcinoma in situ and microinvasive squamous cell carcinoma of the cervix early in pregnancy. Although she had a successful outcome from the management appr...
Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:July 18, 2007
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Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:April 5, 2007
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Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:March 25, 2007
In our last post we discussed the high frequency of early pregnancy losses in first conceptions that probably results from a naive maternal immune response to the fetal tissues; and also the high frequency of chromosomal abnormalities as the most ...
Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:March 22, 2007
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Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:February 23, 2007
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Author:Kenneth F. Trofatter, Jr., MD, PhD
Date:February 14, 2007
The guidelines for weight gain during pregnancy are pretty straightforward:.
Author:Tara Gidus, MS, RD, CSSD, LD/N
Date:June 14, 2007
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