Tuesday, February 14, 2012
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Pernicious Anemia Learning Center

Too little vitamin B12 gradually causes nervous system (neurological) problems. The neurological effects may be seen before anemia is diagnosed.
Source:ADAM
Date:November 23, 2008
Intrinsic factor is produced by specialized cells within the stomach called parietal cells. When these parietal cells shrink in size (atrophy), they produce less and less intrinsic factor. Eventually, the parietal cells stop functioning altogether...
Source:Gale Encyclopedia of Medicine
Anemia is a condition in which the body does not have enough healthy red blood cells. Red blood cells provide oxygen to body tissues. Hemoglobin is the oxygen-carrying protein inside red blood cells. It gives red blood cells their red color. Peopl...
Source:ADAM
Date:April 5, 2009
Anemia is a condition characterized by abnormally low levels of healthy red blood cells or hemoglobin.
Source:Gale Encyclopedia of Alternative Medicine
Anemia is a blood disorder characterized by abnormally low levels of healthy red blood cells (RBCs) or reduced hemoglobin (Hgb), the iron-bearing protein in red blood cells that delivers oxygen to tissues throughout the body. Reduced blood cell vo...
Source:Gale Encyclopedia of Children's Health
Anemia is characterized by an abnormally low number of red blood cells in the circulating blood. It frequently affects patients with cancer. In fact, in many cancer diagnoses such as multiple myeloma and acute leukemia , the presence of anemia may...
Source:Gale Encyclopedia of Cancer
Anemia is a condition characterized by abnormally low levels of healthy red blood cells or hemoglobin (the component of red blood cells that delivers oxygen to tissues throughout the body).
Source:Gale Encyclopedia of Nursing and Allied Health
Anemia is a condition characterized by abnormally low levels of healthy red blood cells or hemoglobin (the component of red blood cells that delivers oxygen to tissues throughout the body).
Source:Gale Encyclopedia of Medicine
Deficiency of red cells, or hemoglobin, in the blood. Anemia is a medical condition in which the quantity of red blood cells falls below an acceptable level. Red blood cells, produced in the bone marrow, contain hemoglobin, the component of blood ...
Source:Gale Encyclopedia of Childhood and Adolescence
Anemia affects more than 30 percent of the world's population, and it is one of the most important worldwide health problems. It has a significant prevalence in both developing and industrialized nations. Causes of anemia include nutritional defic...
Source:Gale Nutrition and Well-Being A to Z
Fatigue is a feeling of weariness, tiredness, or lack of energy.
Source:ADAM
Date:August 3, 2009
Fatigue is physical and/or mental exhaustion that can be triggered by stress , medication, overwork, or mental and physical illness or disease.
Source:Gale Encyclopedia of Alternative Medicine
Fatigue may be defined as a subjective state in which one feels tired or exhausted, and in which the capacity for normal work or activity is reduced. There is, however, no commonly accepted definition of fatigue when it is considered in the contex...
Source:Gale Encyclopedia of Neurological Disorders
Fatigue may be defined as a subjective state in which one feels tired or exhausted, and in which the capacity for normal work or activity is reduced. There is, however, no commonly accepted definition of fatigue when it is considered in the contex...
Source:Gale Encyclopedia of Mental Disorders
Fatigue is physical and/or mental exhaustion that can be triggered by stress , medication, overwork, or mental and physical illness or disease.
Source:Gale Encyclopedia of Medicine
Fatigue is a feeling of exhaustion or loss of strength. The duration of fatigue for a patient with cancer has been found to last from one to two times the length of time between diagnosis and completion of treatment, so it is common for fatigue to...
Source:Gale Encyclopedia of Cancer
Being tired is the familiar aftermath of physical exertion, prolonged labor or lack of sleep. When does being tired become a symptom of a condition? Fatigue, malaise, lassitude, exhaustion are all subtle variations of the same subjective feelings of not having enough energy to meet the demands of one's life.
Source:Healthline
Date:September 30, 2007
Numbness and tingling are decreased or abnormal sensations caused by altered sensory nerve function.
Source:Gale Encyclopedia of Medicine
Paleness is an abnormal loss of color from normal skin or mucous membranes.
Source:ADAM
Date:April 13, 2009
Swallowing pain refers to pain while swallowing, which may be felt high in the neck or lower down behind the breastbone. It is most often a strong feeling of uncomfortable squeezing and burning, and may be a symptom of a serious disorder. See also...
Source:ADAM
Date:October 20, 2009
The heart rate, usually measured by checking the arterial pulse or sounds counting the times of the heart beat, is considered one of the vital signs. Vital signs – body temperature, pulse, breathing rate, and blood pressure provide information about the state of health of a person and, if abnormal, offer clues to problems.
Source:Healthline
Date:September 30, 2007
Pain is a universal human experience. The International Association for the Study of Pain (IASP) defines pain as "an unpleasant sensory and emotional experience associated with actual or potential tissue damage or described in terms of such damage...
Source:Gale Encyclopedia of Neurological Disorders
Pain, medically termed "nociception," is a response to noxious stimuli that is conveyed to the brain by sensory neurons . The discomfort signals actual or impending injury to the body. However, pain is more than a sensation, or the physical awaren...
Source:Gale Encyclopedia of Nursing and Allied Health
Pain is an unpleasant feeling that is conveyed to the brain by sensory neurons. The discomfort signals actual or potential injury to the body. However, pain is more than a sensation, or the physical awareness of pain; it also includes perception, ...
Source:Gale Encyclopedia of Medicine
Pain is an unpleasant feeling that is conveyed to the brain by nerves in the body.
Source:Gale Encyclopedia of Children's Health
Pain is an unpleasant feeling that is conveyed to the brain by sensory neurons. The discomfort signals actual or potential injury to the body. However, pain is more than a sensation, or the physical awareness of pain; it also includes perception, ...
Source:Gale Encyclopedia of Alternative Medicine
Diarrhea is loose, watery, and frequent stool. Diarrhea is considered chronic (long-term) when you have had loose or frequent stools for more than 4 weeks.
Source:ADAM
Date:February 19, 2009
To most persons, diarrhea means an increased frequency or softer consistency of bowel movements; however, the medical definition is more exact than this. Diarrhea best correlates with an increase in stool weight; stool weights above 300 g per day ...
Source:Gale Encyclopedia of Alternative Medicine
Weakness is a reduction in the strength of one or more muscles.
Source:ADAM
Date:August 8, 2009
Numbness and tingling are abnormal sensations that can occur anywhere in your body, but are often felt in your fingers, hands, feet, arms, or legs.
Source:ADAM
Date:April 21, 2009
Numbness and tingling are decreased or abnormal sensations caused by altered sensory nerve function.
Source:Gale Encyclopedia of Children's Health
Breathing difficulty involves a sensation of difficult or uncomfortable breathing or a feeling of not getting enough air. See also: Difficulty breathing - first aid
Source:ADAM
Date:June 12, 2009
Shortness of breath, or dyspnea, is a feeling of difficult or labored breathing that is out of proportion to the patient's level of physical activity. It is a symptom of a variety of different diseases or disorders and may be either acute or chronic.
Source:Gale Encyclopedia of Medicine
An abnormal sensation is often a signal that there something affecting a nerve or the nervous system. These sensations are often difficult to describe and are subjective, that is, experienced by the patient but may be difficult for the provider to diagnose and treat.
Source:Healthline
Date:September 30, 2007
Anorexia is characterized by a loss of appetite or lack of desire to eat.
Source:Gale Encyclopedia of Cancer
Bleeding gums can be a sign that you are at risk for, or already have, gum disease. However, persistent gum bleeding may be due to serious medical conditions such as leukemia and bleeding and platelet disorders.
Source:ADAM
Date:May 28, 2008
Personality changes are alterations in the behavior, thinking and interactions of a person from their established character. These changes may be indicative of chemical dependencies, psychiatric illness, dementia, trauma, illness, altered body chemistry or temperature, or poisoning.
Source:Healthline
Date:November 30, 2007
Fever is the temporary increase in the body's temperature, in response to some disease or illness. A child has a fever when their temperature is at or above one of these levels: 100.4 F (38 C) measured in the bottom (rectally; 99.5 F(37.5 C) measu...
Source:ADAM
Date:December 1, 2009
Unsteady gait is a symptom of instability while walking. Problems with walking can be due to disease or injury to the legs, feet, spine, or brain.
Source:Healthline
Date:November 30, 2007
Gait and balance problems exist when a disease process, trauma, or aging result in the inability to control one's center of gravity (COG) over the base of support (BOS) in static or dynamic tasks and environments.
Source:Gale Encyclopedia of Nursing and Allied Health
Gait or walking is a coordinated action of the neuromuscular and musculoskeletal systems. The coordination of muscle contraction , joint movement, and sensory perception allows the human body to move in the environment. Individuals with neuromuscu...
Source:Gale Encyclopedia of Nursing and Allied Health
Gait training refers to helping a patient relearn to walk safely and efficiently. Gait training is usually done by rehabilitation specialists who evaluate the abnormalities in the person's gait and employ such treatments as strengthening and balan...
Source:Gale Encyclopedia of Nursing and Allied Health
Sensations are carried from the extremities of the body to the brain via neurons in the spinal cord. If the blood supply to the nerves is decreased, it can produce the feeling that “my hand fell asleep”.
Source:Healthline
Date:September 30, 2007
Tongue problems include pain, swelling, or a change in how the tongue looks.
Source:ADAM
Date:March 3, 2009
An arrhythmia is a disorder of the heart rate (pulse) or heart rhythm, such as beating too fast (tachycardia), too slow (bradycardia), or irregularly.
Source:ADAM
Date:May 15, 2008
An arrhythmia is an abnormality in the heart's rhythm, or heartbeat pattern. The heartbeat can be too slow, too fast, have extra beats, skip a beat, or otherwise beat irregularly.
Source:Gale Encyclopedia of Medicine
Sensations are carried from the extremities of the body to the brain via neurons in the spinal cord. If the blood supply to the nerves is or if the nerve is otherwise damaged or its function affected, it can produce the feeling that “my finger fell asleep”.
Source:Healthline
Date:September 30, 2007
Many people experience feel short of breath during strenuous activity if they are not accustomed to exercise. If you have a sudden onset of difficulty breathing doing a normal routine, it may be a medical emergency.
Source:Healthline
Date:September 30, 2007
Sensations are carried from the extremities of the body to the brain via neurons in the spinal cord. If the blood supply to the nerves is decreased temporarily, it can produce the feeling that “my leg fell asleep”.
Source:Healthline
Date:September 30, 2007
Sensations are carried from the extremities of the body to the brain via neurons in the spinal cord. If the blood supply to the nerves is decreased, it can produce the feeling that “my toe fell asleep”.
Source:Healthline
Date:September 30, 2007
Walking abnormalities are unusual and uncontrollable walk patterns, usually caused by diseases or injuries to the legs, feet, brain, spine, or inner ear.
Source:ADAM
Date:March 26, 2009
Impaired smell is the partial or total loss of the sense of smell.
Source:ADAM
Date:September 9, 2009
Sensations are carried from the extremities of the body to the brain via neurons in the spinal cord. If the blood supply to the nerves is decreased, it can produce the feeling that “my foot fell asleep”.
Source:Healthline
Date:September 30, 2007
The heart rate, usually measured by checking the arterial pulse or sounds counting the times of the heart beat, is considered one of the vital signs. Vital signs – body temperature, pulse, breathing rate, and blood pressure provide information about the state of health of a person and, if abnormal,offer clues to problems.
Source:Healthline
Date:September 30, 2007
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