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Paroxysmal Nocturnal Hemoglob... : Causes

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Causes List

Causes could include:
  • mutation in a hematopoietic stem cell

Causes Overview Articles

Paroxysmal nocturnal hemoglobinuria (PNH)
Persons with this disease have blood cells that are missing a gene called PIG-A. This gene allows a substance called glycosyl-phosphatidylinositol (GPI) to help certain proteins stick to cells.
Source:ADAM
Date:November 10, 2008
Paroxysmal nocturnal hemoglobinuria
Mutations in any of 10 different genes can affect the production of GPI. Only one gene, however, is always altered in PNH.
Source:Gale Encyclopedia of Genetic Disorders Part I
Paroxysmal Nocturnal Hemoglobinuria
Mutations in any of 10 different genes can affect the production of GPI. Only one gene, however, is always altered in PNH.
Source:Gale Encyclopedia of Genetic Disorders Part II
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