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Basic Info
Symptoms
Early-onset Krabbe disease: Changing muscle tone from floppy to rigid (decerebrate posturing; Hearing loss that leads...
Causes
A defect in the GALC gene causes Krabbe disease. Persons with this gene defect do not make enough of a substance call...
Tests
An exam of the retina in the eye may show damage to the optic nerve. There may be signs or deafness and abnormal post...
Treatments
There is no specific treatment for Krabbe disease. Some people have had a bone marrow transplant in the early stages ...
Complications
This disease damages the central nervous system. It can cause: Blindness; Deafness; Severe problems with muscle tone....
Prevention
Genetic counseling is recommended for persons with a family history of Krabbe disease who are considering having chil...
Doctor Specialties
Call your health care provider if your child develops symptoms of this disorder. Seizures, loss of consciousness, or ...
Basic Info
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