Hereditary Spherocytosis Learning Center

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Welcome

Congenital spherocytic anemia is a disorder of the red blood cell membrane that leads to sphere-shaped red blood cells, and chronic hemolytic anemia (premature breakdown of red blood cells).

Basic Info

Symptoms
Jaundice; Pallor; Shortness of breath; Fatigue; Weakness; Irritability in children.
Causes
This disorder is caused by a defective gene. The defect results in an abnormal red blood cell membrane. The affected ...
Tests
Physical exam reveals enlarged spleen; Reticulocyte count is elevated; Blood smear shows spherocytes; Complete blood ...
Treatments
Surgery to remove the spleen (splenectomy) cures the anemia of spherocytosis. Although the abnormal cell defect conti...
Complications
Development of gallstones from the pigment that comes from the destroyed red blood cells; Much lower red blood cell p...
Prevention
This is an inherited disorder and may not be preventable. Being aware of your risk, such as a family history of the d...
Doctor Specialties
Call your health care provider for an appointment if your symptoms get worse, do not improve with treatment, or if yo...

Basic Info

Related Topics

Genetic Disorders

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