Hereditary Angioedema Learning Center

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Welcome

Hereditary angioedema is an inherited abnormality of the immune system that causes swelling, particularly of the face, and abdominal cramping. Also see angioedema .

Basic Info

Symptoms
Swelling in the arms, legs, lips, eyes, tongue, or throat; Airway blockage (involves throat swelling and sudden hoarsen...
Causes
Hereditary angioedema (HAE) is caused by low levels or improper function of a protein called C1 inhibitor. This problem...
Tests
Decreased C1 inhibiting factor activity; Decreased C4 and C2 levels.
Treatments
Antihistamines and other related treatments are of limited benefit in hereditary angioedema. Attenuated androgens, whic...
Drugs
  • aminocaproic acid
  • danazol
  • epinephrine
Risk Factors
  • Anxiety
  • Dental Procedures
  • Family History
Complications
Swelling of the airways may be deadly.
Prevention
Genetic counseling may be beneficial for prospective parents with a family history of hereditary angioedema.
Doctor Specialties
Call your health care provider if you are considering having children and have a family history of this condition, or i...

Basic Info

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