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Hemophilia A Learning Center

Bleeding into joints, with associated pain and swelling; Blood in the urine or stool; Bruising; Gastrointestinal tract and urinary tract hemorrhage; Prolonged bleeding from cuts, tooth extraction, and surgery; Spontaneous bleeding;
Source:ADAM
Date:March 21, 2008
In the case of severe hemophilia, the first bleeding event usually occurs prior to eighteen months of age. In some babies, hemophilia is suspected immediately, when a routine circumcision (removal of the foreskin of the penis) results in unusually...
Source:Gale Encyclopedia of Genetic Disorders Part I
Hemophilia A and B are both caused by a genetic defect present on the X chromosome. (Hemophilia C is inherited in a different fashion.) About 70 percent of all people with hemophilia A or B inherited the disease. The other 30 percent develop from ...
Source:Gale Encyclopedia of Children's Health
In the case of severe hemophilia, the first bleeding event usually occurs prior to 18 months of age. In some babies, hemophilia is suspected immediately when a routine circumcision (removal of the foreskin of a penis) results in unusually heavy bl...
Source:Gale Encyclopedia of Nursing and Allied Health
Hemophilia A and B are both caused by a genetic defect present on the X chromosome. (Hemophilia C is inherited in a different fashion.) About 70% of all people with hemophilia A or B inherited the disease. The other 30% develop from a spontaneous ...
Source:Gale Encyclopedia of Medicine
In the case of severe hemophilia, the first bleeding event usually occurs prior to eighteen months of age. In some babies, hemophilia is suspected immediately, when a routine circumcision (removal of the foreskin of the penis) results in unusually...
Source:Gale Encyclopedia of Genetic Disorders Part II
Bleeding refers to the loss of blood. Bleeding can happen inside the body (internally) or outside the body (externally. It may occur: Inside the body when blood leaks from blood vessels or organs; Outside the body when blood flows through a natura...
Source:ADAM
Date:January 15, 2009
Gastrointestinal (GI) bleeding refers to any bleeding that starts in the gastrointestinal tract, which extends from the mouth to the anus. The amount of bleeding can range from nearly undetectable to acute, massive, and life threatening. Bleeding ...
Source:ADAM
Date:January 28, 2009
GI bleeding studies uses radioactive materials in the investigation of bleeding from the gastrointestinal (GI) tract. These studies go under various names such as "GI bleeding scans" or "Tagged red blood cell scans." They are performed and interpr...
Source:Gale Encyclopedia of Medicine
Joint swelling is the buildup of fluid in the soft tissue surrounding the joint.
Source:ADAM
Date:August 12, 2008
Rectal bleeding is a common problem, often caused by constipation, anal fissures or hemorrhoids. It can be an indication of serious occult disease and should be evaluated by a physician.
Source:Healthline
Date:November 30, 2007
Blood in your urine, or hematuria, can be classified as microscopic or gross. Microscopic hematuria is when there is very little blood in the urine and it can only be seen with a microscope; Gross hematuria is when there is enough blood in the uri...
Source:ADAM
Date:September 30, 2009
Most of us get bruises from bumping into something from time to time. Bruising sometimes increases with age, especially in women as the capillary walls become more fragile and the skin becomes thin.
Source:Healthline
Date:November 30, 2007
Bloody stools often indicate an injury or disorder in the digestive tract. Your doctor may use the term "melena" to describe black, tarry, and foul-smelling stools or "hematochezia" to describe red- or maroon-colored stools.
Source:ADAM
Date:January 11, 2009
Bleeding disorders are a group of conditions in which there is a problem with the body's blood clotting process. These disorders can lead to heavy and prolonged bleeding after an injury. Bleeding can also begin on its own. See also: Acquired plate...
Source:ADAM
Date:March 2, 2009
Pain is a universal human experience. The International Association for the Study of Pain (IASP) defines pain as "an unpleasant sensory and emotional experience associated with actual or potential tissue damage or described in terms of such damage...
Source:Gale Encyclopedia of Neurological Disorders
Pain, medically termed "nociception," is a response to noxious stimuli that is conveyed to the brain by sensory neurons . The discomfort signals actual or impending injury to the body. However, pain is more than a sensation, or the physical awaren...
Source:Gale Encyclopedia of Nursing and Allied Health
Pain is an unpleasant feeling that is conveyed to the brain by sensory neurons. The discomfort signals actual or potential injury to the body. However, pain is more than a sensation, or the physical awareness of pain; it also includes perception, ...
Source:Gale Encyclopedia of Medicine
Pain is an unpleasant feeling that is conveyed to the brain by sensory neurons. The discomfort signals actual or potential injury to the body. However, pain is more than a sensation, or the physical awareness of pain; it also includes perception, ...
Source:Gale Encyclopedia of Alternative Medicine
Pain is an unpleasant feeling that is conveyed to the brain by nerves in the body.
Source:Gale Encyclopedia of Children's Health
Anemia is a condition in which the body does not have enough healthy red blood cells. Red blood cells provide oxygen to body tissues. Hemoglobin is the oxygen-carrying protein inside red blood cells. It gives red blood cells their red color. Peopl...
Source:ADAM
Date:April 5, 2009
Anemia is a condition characterized by abnormally low levels of healthy red blood cells or hemoglobin.
Source:Gale Encyclopedia of Alternative Medicine
Anemia is characterized by an abnormally low number of red blood cells in the circulating blood. It frequently affects patients with cancer. In fact, in many cancer diagnoses such as multiple myeloma and acute leukemia , the presence of anemia may...
Source:Gale Encyclopedia of Cancer
Anemia is a blood disorder characterized by abnormally low levels of healthy red blood cells (RBCs) or reduced hemoglobin (Hgb), the iron-bearing protein in red blood cells that delivers oxygen to tissues throughout the body. Reduced blood cell vo...
Source:Gale Encyclopedia of Children's Health
Anemia is a condition characterized by abnormally low levels of healthy red blood cells or hemoglobin (the component of red blood cells that delivers oxygen to tissues throughout the body).
Source:Gale Encyclopedia of Nursing and Allied Health
Deficiency of red cells, or hemoglobin, in the blood. Anemia is a medical condition in which the quantity of red blood cells falls below an acceptable level. Red blood cells, produced in the bone marrow, contain hemoglobin, the component of blood ...
Source:Gale Encyclopedia of Childhood and Adolescence
Anemia is a condition characterized by abnormally low levels of healthy red blood cells or hemoglobin (the component of red blood cells that delivers oxygen to tissues throughout the body).
Source:Gale Encyclopedia of Medicine
Anemia affects more than 30 percent of the world's population, and it is one of the most important worldwide health problems. It has a significant prevalence in both developing and industrialized nations. Causes of anemia include nutritional defic...
Source:Gale Nutrition and Well-Being A to Z
Fatigue is a feeling of weariness, tiredness, or lack of energy.
Source:ADAM
Date:August 3, 2009
Fatigue is physical and/or mental exhaustion that can be triggered by stress , medication, overwork, or mental and physical illness or disease.
Source:Gale Encyclopedia of Alternative Medicine
Fatigue may be defined as a subjective state in which one feels tired or exhausted, and in which the capacity for normal work or activity is reduced. There is, however, no commonly accepted definition of fatigue when it is considered in the contex...
Source:Gale Encyclopedia of Neurological Disorders
Fatigue is physical and/or mental exhaustion that can be triggered by stress , medication, overwork, or mental and physical illness or disease.
Source:Gale Encyclopedia of Medicine
Fatigue may be defined as a subjective state in which one feels tired or exhausted, and in which the capacity for normal work or activity is reduced. There is, however, no commonly accepted definition of fatigue when it is considered in the contex...
Source:Gale Encyclopedia of Mental Disorders
Fatigue is a feeling of exhaustion or loss of strength. The duration of fatigue for a patient with cancer has been found to last from one to two times the length of time between diagnosis and completion of treatment, so it is common for fatigue to...
Source:Gale Encyclopedia of Cancer
Weakness is a reduction in the strength of one or more muscles.
Source:ADAM
Date:August 8, 2009
A bruise is an area of skin discoloration. A bruise occurs when small blood vessels break and leak their contents into the soft tissue beneath the skin.
Source:ADAM
Date:May 2, 2009
Bruises, or ecchymoses, are a discoloration and tenderness of the skin or mucous membranes due to the leakage of blood from an injured blood vessel into the tissues. Pupura refers to bruising as the result of a disease condition. A very small brui...
Source:Gale Encyclopedia of Alternative Medicine
Bruises, or ecchymoses, are a discoloration and tenderness of the skin or mucous membranes due to the leakage of blood from an injured blood vessel into the tissues. Pupura refers to bruising as the result of a disease condition. A very small brui...
Source:Gale Encyclopedia of Medicine
Bruises, or ecchymoses, are a discoloration and tenderness of the skin or mucous membranes due to the leakage of blood from an injured blood vessel into the tissues. Purpura refers to bruising as the result of a disease condition. A very small bru...
Source:Gale Encyclopedia of Children's Health
Joint pain can affect one or more joints. See also: Arthritis (inflammation of joints; Bursitis; Muscle pain.
Source:ADAM
Date:April 24, 2008
Being tired is the familiar aftermath of physical exertion, prolonged labor or lack of sleep. When does being tired become a symptom of a condition? Fatigue, malaise, lassitude, exhaustion are all subtle variations of the same subjective feelings of not having enough energy to meet the demands of one's life.
Source:Healthline
Date:September 30, 2007
Paleness is an abnormal loss of color from normal skin or mucous membranes.
Source:ADAM
Date:April 13, 2009
A black eye is usually the result of trauma to the head or face – particularly the nose, resulting in bleeding beneath the skin which results in discoloration or bruising. Most black eyes are not serious, but sometimes can be an indicator of a medical emergency, such as a skull fracture.
Source:Healthline
Date:November 30, 2007
Many people experience feel short of breath during strenuous activity if they are not accustomed to exercise. If you have a sudden onset of difficulty breathing doing a normal routine, it may be a medical emergency.
Source:Healthline
Date:September 30, 2007
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