Graft Vs. Host Disease Learning Center

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Welcome

Graft-versus-host-disease is a condition that can occur following bone marrow transplant . The condition may be acute or chronic, mild or severe. Severe cases can often be life-threatening. See also transplant rejection...

Basic Info

Symptoms
Symptoms in both acute and chronic GVHD range from mild to severe. Common acute symptoms include: Abdominal pain or cra...
Causes
GVHD occurs in a bone marrow transplant involving a donor and a recipient. The bone marrow makes all types of blood cel...
Tests
The tests done usually depend on the symptoms, but may include: Gastrointestinal endoscopy, with or without a biopsy; L...
Treatments
The goal of treatment is to suppress the immune response without damaging the new marrow. Medicines commonly used inclu...
Drugs
  • acitretin
  • cycloSPORINE
  • Gamma globulin
Alternative Therapies
  • Acupuncture
  • Massage
  • Meditation
Risk Factors
  • Allogeneic Bone Marrow Transplantation
  • Older Population
  • Tissue incompatibilities
Complications
Cholestasis; Moderate-to-severe damage to the liver, lung, or digestive tract; Severe infection; Severe lung disease.
Prevention
Before a transplant, your blood type and tissue type will be carefully matched with eligible donors. This matching will...
Doctor Specialties
If you have had a bone marrow transplant and are no longer in the transplant center, call your health care provider imm...

Basic Info

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