Gigantism Learning Center

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Welcome

Gigantism is an excessive secretion of growth hormone during childhood, before the closure of the bone growth plates. This excess growth hormone causes overgrowth of the long bones and very tall stature.

Basic Info

Symptoms
Excessive growth during childhood; Frontal bossing and a prominent jaw; Thickening of the facial features; Disproportio...
Causes
The cause of excess growth hormone secretion is most often a benign pituitary gland tumor. Gigantism may also be caused...
Tests
An increase in insulin growth factor-I (IGF-I) levels; A failure to suppress serum growth hormone (GH) levels after an ...
Treatments
In pituitary tumors with well-defined borders, surgery is the treatment of choice and is curative is about 80% of cases...
Drugs
  • bromocriptine
  • cabergoline
  • octreotide
Risk Factors
  • Childhood
  • McCune-Albright Syndrome
  • Multiple Endocrine Neoplasia Type 1
Complications
The development of secondary sexual characteristics may be delayed; Surgery and radiation can both lead to deficiencies...
Doctor Specialties
Call your health care provider if signs of excessive growth during childhood are present.

Basic Info

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