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Angioedema

Angioedema is a swelling similar to urticaria (hives), but the swelling is beneath the skin rather than on the surface. The swellings are called welts. The welts usually occurs around the eyes and lips. They may also be found on the hands, feet, and throat. Angioedema can result from certain allergies . See also: Hereditary angioedema

Source:ADAM

Date:April 28, 2008

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Hereditary angioneurotic edema

Hereditary angioneurotic edema (HANE) is a nonsex-linked (autosomal) dominant disease that results from mutations in a gene responsible for producing one of the proteins responsible for human immunity. This disease is also known as hereditary angioedema (HAE) or hereditary C1 inhibitor deficiency because it is a deficiency of the protein (C1-INH) that inhibits the action of the enzyme known as C1 which causes this disease.

Source:Gale Encyclopedia of Genetic Disorders Part I

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