Factor V Deficiency : Causes

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Normal blood coagulation is a complex process involving as many as 20 different proteins in blood plasma, which are known as blood coagulation factors. A series of complex chemical reactions using these factors takes place very rapidly to form a p...
Source:ADAM
Date:March 24, 2008
Factor V Leiden thrombophilia occurs when a specific gene on the long arm of chromosome one is changed or mutated. This gene is called F5. Every person has approximately 30,000–35,000 genes that tell our bodies how to form and function. Each...
Source:Gale Encyclopedia of Genetic Disorders Part I
An abnormal gene on one of the autosomal chromosomes (one of the first 22 "non-sex" chromosomes) from each parent is required to cause the disease. People with only one abnormal gene in the gene pair are called carriers, but since the gene is recessive they do not exhibit the disease. In other words, the normal gene of the pair can supply the function of the gene so that the abnormal gene is described as acting in a recessive manner. BOTH parents must be carriers in order for a child to have symptoms of the disease. A child who inherits the gene from one parent will be a carrier.
Source:ADAM
Date:May 20, 2008
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