Down Syndrome : Risk Factors

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A change in location. Usually refers to genetic translocations, in which part of a chromosome is transferred to another chromosome. This type of translocation can result in a bigger, flawed, chromosome; in other cases, the two chromosomes will trade pieces with each other. Genetic translocations can cause serious disorders, such as Chronic Myelogenous Leukemia .
Source:ADAM
Date:July 25, 2007
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