Congenital Toxoplasmosis Learning Center

PYRIMETHAMINE (pahy ruh METH uh meen) is an anti-parasitic medicine. It is used to treat and to prevent malaria. This medicine is also used to treat an infection of toxoplasmosis.

Pyrimethamine (single-entity preparation) and fixed-combination preparation containing sulfadoxine and pyrimethamine (Fansidar ® ) have been used for prevention (prophylaxis) of malaria, but are no longer recommended by CDC or others for malaria prevention. Resistance to pyrimethamine is prevalent worldwide; resistance to Fansidar ® is widespread in certain areas (e.g., Amazon basin area of South America, Southeast Asia, other parts of Asia, large parts of Africa). Consider use of Fansidar ® for malaria prophylaxis only in individuals traveling to areas where chloroquine-resistant Plasmodium falciparum malaria is endemic and susceptible to the drug and only when other antimalarials (chloroquine, mefloquine, doxycycline, fixed combination of atovaquone and proguanil hydrochloride [Malarone ® ]) are unavailable or contraindicated.

SULFADIAZINE (sul fa DYE a zeen) is an sulfonamide antibiotic. It is used to treat many different kinds of bacterial infections, like those of the brain, ears, and urinary tract. It is also used to prevent infections in people who are at risk. It ...

Antibacterial; intermediate-acting sulfonamide.

PREDNISONE (PRED ni sone) is a corticosteroid. It is commonly used to treat inflammation of the skin, joints, lungs, and other organs. Common conditions treated include asthma, allergies, and arthritis. It is also used for other conditions, such a...

PREDNISONE (PRED ni sone) is a corticosteroid. It is commonly used to treat inflammation of the skin, joints, lungs, and other organs. Common conditions treated include asthma, allergies, and arthritis. It is also used for other conditions, such a...

Synthetic glucocorticoid; minimal mineralocorticoid activity.