Ankylosing Spondylitis : Causes
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Causes could include:
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No known cause
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The cause of ankylosing spondylitis is unknown, but genes seem to play a role. The disease most frequently begins between ages 20 and 40, but may begin before age 10. It affects more males than females. Risk factors include a family history of ank...
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AS is considered a multifactorial disorder, or one that is the result of both genetic and environmental factors interacting. Two genes have been identified that confer susceptibility to AS, both of which are forms of an HLA gene on chromosome 6. S...
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AS is considered a multifactorial disorder, or one that is the result of both genetic and environmental factors interacting. Two genes have been identified that confer susceptibility to AS, both of which are forms of an HLA gene on chromosome 6. S...
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Doctors usually diagnose the disease simply by the patient's report of pain and stiffness. Doctors also review spinal and pelvic x rays since involvement of the hip and pelvic joints is common and may be the first abnormality seen on the x ray. Th...
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Genetics play an important role in the disease, but the cause of AS is still unknown. More than 90% of patients have a gene called HLA-B27, but only 10-15% of those who inherit the gene develop the disease. Symptoms of AS include: low back and hip...
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