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Ankylosing Spondylitis : Causes

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Causes List

Causes could include:
  • No known cause

Causes Overview Articles

Ankylosing spondylitis
It affects more males than females. Risk factors include a family history of ankylosing spondylitis and male gender.
Source:ADAM
Date:April 24, 2008
Ankylosing Spondylitis
AS is considered a multifactorial disorder, or one that is the result of both genetic and environmental factors interacting. Two genes have been identified that confer susceptibility to AS, both of which are forms of an HLA gene on chromosome 6.
Source:Gale Encyclopedia of Genetic Disorders Part II
Ankylosing spondylitis
AS is considered a multifactorial disorder, or one that is the result of both genetic and environmental factors interacting. Two genes have been identified that confer susceptibility to AS, both of which are forms of an HLA gene on chromosome 6.
Source:Gale Encyclopedia of Genetic Disorders Part I
Ankylosing Spondylitis
Doctors usually diagnose the disease simply by the patient's report of pain and stiffness. Doctors also review spinal and pelvic x rays since involvement of the hip and pelvic joints is common and may be the first abnormality seen on the x ray.
Source:Gale Encyclopedia of Alternative Medicine
Ankylosing Spondylitis
Genetics play an important role in the disease, but the cause of AS is still unknown. More than 90% of patients have a gene called HLA-B27, but only 10-15% of those who inherit the gene develop the disease.
Source:Gale Encyclopedia of Medicine
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