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Adrenoleukodystrophy : Causes

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Causes could include:
Adrenoleukodystrophy is passed down from parents to their children as an X-linked genetic trait. It therefore affects mostly males, although some women who are carriers can have milder forms of the disease.
Source:ADAM
Date:November 12, 2007
ALD is caused by a mutation in a gene called the ALD gene. Genes contain the instructions for how the body grows and develops before and after a person is born.
Source:Gale Encyclopedia of Genetic Disorders Part I
ALD is caused by a mutation in a gene called the ALD gene. Genes contain the instructions for how the body grows and develops before and after a person is born.
Source:Gale Encyclopedia of Genetic Disorders Part II
ALD causes problems in the peroxisomes, tiny cellular structures that are involved in breaking down large molecules of fats into smaller ones that can be used by the body. In ALD, the peroxisomes cannot break down a type of fat called very long ch...
Source:Gale Encyclopedia of Neurological Disorders
The genetic defect in ALD causes a decrease in the ability to degrade very long chain fatty acids. These build up in the adrenal glands, brain, plasma, and fibroblasts.
Source:Gale Encyclopedia of Medicine
In a strict sense, mutations are changes in genes not caused by genetic recombination. A change in the base sequence of DNA, for example, represents a mutational change.
Source:Gale Encyclopedia of Genetic Disorders Part I
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