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The treatment choices for each person depend on the size and location of the tumor, the results of lab tests, and the stage or extent of the disease. A doctor also considers the person's age and general health when making recommendations about a treatment.
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An operation called an adrenalectomy is commonly used to treat adrenal cancer, and offers the best chance for cure. During this surgery, the doctor takes out the adrenal gland. Surrounding tissues and lymph nodes may also be removed. Sometimes surgeons will remove tumors that have spread to other parts of the body (metastasized).
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The drugs used in chemotherapy attack and kill cells that divide quickly, including cancer cells and some normal cells. How chemotherapy drugs affect those normal cells is based on the types of drugs used and the person getting the drugs. In general, chemotherapy is not very effective for adrenal cancer, and if at all possible, surgery should be considered the treatment of choice. Chemotherapy can be tried for cancer that has come back (recurred) or spread to other parts of the body (metastasis). The most commonly used chemotherapy for adrenal cancer are mitotane, cisplatin, etoposide, and doxorubicin.
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Radiation therapy, also called radiotherapy, uses high-energy radiation to kill cancer cells. Radiation can be used before surgery to shrink the size of a tumor, making surgery easier and more effective. Radiation therapy can also be used to treat body parts that the tumor has spread to (metastasis).
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