Does the e-cigarette deliver nicotine?
There is currently considerable interest (hype?) in the e-cigarette, and I have written about it before. Last weekend I was walking through our local shopping mall in New Jersey with my 8-year old daughter when she tugged at my arm and said “dad, dad, theres a man smoking over there.” I told her that couldn’t be true because people arnt allowed to smoke inside the mall, but she insisted. On looking over I was surprised to see that sure enough, someone was standing next to a booth and appeared to be puffing away on a cigarette. So we walked over to investigate, and found out that in fact it was an e-cigarette and he was selling the product at the booth. We chatted and he showed me the product which actually looks very impressive. I had already purchased an earlier version a couple of years ago, which was more stogie cigar-sized, but this one looked and puffed very much like a cigarette and was also considerably less expensive than the earlier model.
But whenever discussing this product, to me the first and most critical question (after …”whats in the vapor and might it harm my health?”) is, “does it deliver enough nicotine to satisfy nicotine cravings? “ Until I came to this conference, I hadn’t met anyone who had completed a study that included measurement of blood nicotine levels in people using the e-cigarette. This question is critical because cigarette smokers are used to receiving a boost in blood nicotine levels of at least 10 ng/ml from each cigarette, and for a product to have any chance of effectively reducing craving for or replacing cigarettes it needs to come close to that level of nicotine delivery.
But I was lucky enough to bump into Dr Murray Laugesen, a tobacco control expert from New Zealand who has been one of the foremost proponents of the product. He showed me a preliminary report on the e-cigarette which was being presented at the conference. Full details of the study will be presented in a formal publication sometime in the future, but for right now the main conclusion is that although the e-cigarette CONTAINS a reasonable amount of nicotine it actually DELIVERS very little nicotine to the user, and certainly much much less that can be obtained from smoking. To my mind this relegates the status of this product to that of a very nice and cleverly designed theatre prop, and unfortunately not a product that is likely to be highly effective in helping smokers to quit smoking.
As always, if you are interested in using a product to assist you in quitting smoking, your best bet is to use a product that has been approved by the medicines licensing agency in your country as safe and effective for that purpose (e.g. in the U.S. that would be the FDA).
For more information about Dr Laugesen’s work on the e-cigarette, visit:
http://www.healthnz.co.nz/ecigarette.htm
Labels: cigarette, e-cigarette, jonathan foulds, nicotine



3 Comments:
At Fri May 01, 10:43:00 AM 2009,
Anonymous said…
Thanks Jonathan. Here are the details:
In a poster presented at the 2009 Annual Meeting of the Society for Research on Nicotine and Tobacco, Bullen, Glover, Laugesen, Lin, McRobbie, and Thornley report that after 9 participants used the Ruyan device (16 mg cartridge) for 5 minutes, peak plasma nicotine concentration was 1.3 ng/ml (95% confidence interval = 0.0 to 2.6). In contrast, for those same participants, a cigarette produced a peak plasma nicotine concentration of 13.4 ng/ml (95% CI = 6.5-20).
These data, if they are valid and can be replicated, provide little support for the manufacturers' claim that the devices can do what they are marketed to do: deliver a physiologically active nicotine dose to the lung.
Tom E
At Sat Jul 25, 06:35:00 PM 2009,
Thanasis said…
Some people are addicted mainly to the habit, that is the action of smoking itself. Some usually just like the flavor, that is me for example. I only smoke around 5 'light' cigs a day, but still want to quit. Although there is no unbiased way to say I m not addicted to nicotine, I think that a nicely flavored analog would do as good for me, even with 0mg nicotine. Do you think the e-cig would be a good start for the beginning, until I quite completely?
Thanks a lot
T.K.
At Thu Oct 29, 11:15:00 AM 2009,
xackley said…
Even Mark Twain would testify to the effectiveness of the E-Cigarette, if he were here to enjoy one. The only reason I would ever smoke another cigarette would be if the E-cigarette was made illegal, and could not be found on a black market.
When I purchased my first e-cigarette, I had no intention of quitting smoking. The e-cigarette is simply a better way to "smoke". With 37 years experience burning about 20 cigarettes a day, I have zero urge to ever light one again.
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