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Kenneth F. Trofatter, Jr., MD, PhDPregnancy and Childbirth
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Prematurity Awareness Day - 2008

Kenneth F. Trofatter, Jr., MD, PhD
Today is Prematurity Awareness Day. At a local press conference sponsored by the March of Dimes, I had the opportunity to discuss some of my thoughts on this subject with a reporter. When I started my residency, the prematurity rate sat between 8% and 9%. Today one in every eight babies (530,000 per year) in the U.S. is born prematurely and in my home state of South Carolina the rate is even higher – one in five to six babies. (Incidentally, during the same time period since my residency, cesarean delivery rates have gone from about 12% to 35%).

Complications related to prematurity now make it the leading cause of death among newborns and during the first year of life – now surpassing birth defects. This holds true despite the remarkable advances that have been made in neonatal care that have pushed survival into the range of 23 weeks gestation. In general, first year medical costs for preterm babies across the board are at least 10 times greater than that for babies born at term. The 2006 Institute of Medicine special report, “Preterm Birth: Causes, Consequences, and Prevention,” concluded preterm birth costs our nation $26 billion annually. Factoring in the continued rise in preterm birth as a percentage of all deliveries, the population increase, the immediate expense related to the acute care of extremely premature neonates (and the ongoing expenses due to complications of prematurity among survivors), the enormous number of late preterm deliveries (and their ongoing expenses due to complications of prematurity!), and the inflation in health care costs, I would wager that the total cost is now much more than twice that annually.

Despite the fact that we have a long list of factors that we know are associated with increased risk for preterm birth, we continue to lose ground in the battle against it. Funding for women’s health initiatives related to prenatal care is inadequate, educational programs that focus on planned pregnancy, preconceptional counseling and early entry to prenatal care, adequate nutrition and weight control, stress reduction, cessation of smoking and other substance abuse, are not widespread enough (nor begun early enough in life), and efforts to scrutinize and control the high rates of labor induction, as well as primary and repeat cesarean deliveries are thwarted by providers, hospitals, and patients themselves.

Especially frustrating to me are the factors over which we could have a significant impact, but where we are falling further and further behind: teen pregnancy rates are the highest they have been in years; obesity is morbidly epidemic and beginning younger and younger in life; patients in our area are presenting later for prenatal care (forget preconceptional care); racial disparities in preterm birth rates are widening; more than 20% of pregnant women in South Carolina continue to smoke; access to care is being deleteriously affected by Medicaid cuts, poorly-controlled Managed Medicaid programs, and a growing percentage of underinsured and completely uninsured women in their reproductive years; and reimbursement for providers of obstetrical care is inadequate to cover expenses when one factors the total amount of time required in patient management during the pregnancy, labor, and delivery and the liability risks and overhead costs associated with that care.

Personally, I support and applaud the efforts of the March of Dimes to address the many issues related to preterm birth. Since 2003, the organization has focused its attention on raising public awareness and expanding programs that provide information and support to families affected by preterm birth. But, this is an effort that will require support, financially and organizationally, at a much higher level if the dismaying trends are to be reversed and a true impact realized.

The first step in this is not necessarily underwriting large research programs to identify the ‘cause’ or a ‘treatment’ for preterm birth. Preterm birth is not a disease, it is the final common pathway of the many factors that variably contribute to it in different individuals. We must, however, continue the efforts by groups such as the March of Dimes to educate patients, providers, employers, and politicians regarding the extent of the problem and its long-term consequences on the health, healthcare costs, and welfare of our people. We must also focus our attention on preventive and ‘therapeutic’ programs to address some of the major issues mentioned above – programs that will improve the general health of women in their prereproductive and reproductive years – improving the prospects that their children will not be destined to repeat the cycles of the prior generations.

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4 Comments:

  • At Sat Nov 15, 09:24:00 AM 2008, Blogger roseyjenni said…

    Hello Dr. T., I'm sorry this question isn't directly related to your post. I am 36 y/o and 5 weeks pregnant. For the past 5 years I have had metrorrhagia due to cervical or endometrial polyps. i never have more than one at a time, they are small, and they often go away by themselves. i've had a few removed. i've been getting a transvag ultrasound about every 6 months to monitor the thickness of my uterine lining re: possible need for d&c - so far not yet. my obgyn won't see me for an appt until week 8 but i have lots of spotting. this is nervewracking - is there any way to tell if the spotting is cervical polyp, endometrial polyp or threatened miscarriage? how elevated is my risk of miscarriage given these circumstances? any feedback would be appreciated!

     
  • At Sun Nov 16, 01:27:00 PM 2008, Anonymous Anonymous said…

    Dear Dr T.:
    I would have loved to post on the First Trimester Screening Blog but that did not seem to work.
    I am 14 weeks pregnant. My 9th pregnancy (5 miscarriages, 3 live children of whom the last 2 were born 4 weeks early).
    This time around we are having dizygotic twins (whew!).
    I have questions concerning my papp-a and free B-hcg levels from the NT screening. My NT values came back normal with 1.2 and 1.6 mm respectively (at 12 weeks). My papp-a came back at 1.5 MoM, same as my free b-hcg (all measurements taken the same day). Both babies measured exactly 12 weeks (don't have the numbers though). My risk for Downs was 1:100 (I am 37 and will be 37 on due date, May 19th, 2009). Risk went down to 1:155 but still below cut-off.
    Of course I am worried about the serum marker values. The counselor I was talking to did not give me an y idea how far off my values are. I thought high risk for Downs would be high HCg and low papp-a. What does it mean to have both low? and how low are my values?
    Thanks so much. Your article on First Screening was very very informative!!!

     
  • At Fri Nov 28, 10:21:00 AM 2008, Blogger Kenneth F. Trofatter, Jr., MD, PhD said…

    To roseyjenni: I am afraid the only way to tell what is going on is to do an examination vaginally and to perform an ultrasound. I wish I ghad my 'crystal ball' but I do not. If the bleeding gets heavier, I am sure your doctor will see you sooner. Best wishes to you and please let us know how things turn out. Dr T

     
  • At Fri Nov 28, 10:27:00 AM 2008, Blogger Kenneth F. Trofatter, Jr., MD, PhD said…

    To anonymous Nov 16: I think the factors driving your risk are your age and the fact you have dizygotic twins (that doubles your risk if the presumption is that they are from separate eggs). The NT measurements are great and the modestly elevated PAPP-A and hCG levels should be well within the normal range for a twin gestation at this time in pregnancy. Odds are in your favor that everything is fine. I am curious, however, about the early deliveries - why did you deliver early? - because if these were the result of premature labor or cervical insufficiency (incompetence), then you will be at increased risk for even earlier delivery with twins. Best wishes and let us know how things turn out. Dr T

     

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