Stability

Storage

Tablets: 15–30°C in tight, light resistant container. Replace cap securely after opening.

Tablets for self-administration: 20–25°C.

2–30°C.

4–30°C in tight, light resistant container.

4–25°C; may be exposed to temperatures up to 30°C.

Protect from light.

Protect from freezing.

Darkening of undiluted injection does not affect potency.

Dilutions in most IV solutions: stable for up to 48 hours at room temperature.

2–25°C. Brief exposure to temperatures up to 40°C does not affect stability.

Protect from light.

Protect from freezing.

Compatible
Amino acids 8.5%
Dextrose 5% in sodium chloride 0.45%
Dextrose 5 or 10% in water
Fat emulsion 10%, IV
Sodium chloride 0.9%
Variable
Dextrose 5% in Ringer’s injection, lactated. (stable for 48 hours)

**Admixture Compatibility**
Compatible
Acetazolamide sodium
Amikacin sulfate
Aminophylline
Chloramphenicol sodium succinate
Chlorothiazide sodium
Ciprofloxacin
Colistimethate sodium
Dexamethasone sodium phosphate
Digoxin
Dobutamine HCl
Dopamine HCl
Doxycycline hyclate
Epinephrine HCl
Erythromycin lactobionate
Fluconazole with ondansetron HCl
Flumazenil
Furosemide
Gentamicin sulfate
Heparin sodium
Isoproterenol HCl
Lidocaine HCl
Lincomycin HCl
Meropenem
Methylprednisolone sodium succinate
Midazolam HCl
Penicillin G potassium
Penicillin G sodium
Polymyxin B sulfate
Potassium chloride
Protamine sulfate
Quinidine gluconate
Sodium nitroprusside
Tobramycin sulfate
Vancomycin HCl
Zidovudine
Incompatible
Amphotericin B
Atracurium besylate
Cefoxitin sodium
Ceftazidime
Ethacrynate sodium
Phytonadione
Variable
Ampicillin sodium
Cefazolin sodium
Cefuroxime sodium
Clindamycin phosphate
Norepinephrine bitartrate

**Y-Site Compatibility**
Compatible
Acyclovir sodium
Alcohol 10% in dextrose 5%
Aldesleukin
Allopurinol sodium
Amifostine
Aminophylline
Amsacrine
Atracurium besylate
Aztreonam
Bivalirudin
Bretylium tosylate
Cefazolin sodium
Cefepime HCl
Cefoxitin sodium
Ceftazidime
Ceftizoxime sodium
Ciprofloxacin
Cisplatin
Cladribine
Clarithromycin
Cyclophosphamide
Cytarabine
Dexmedetomidine HCl
Diltiazem HCl
Dobutamine HCl
Docetaxel
Dopamine HCl
Doxapram HCl
Doxorubicin HCl
Doxorubicin HCl liposome injection
Enalaprilat
Epinephrine HCl
Esmolol HCl
Etoposide phosphate
Fenoldopam mesylate
Fentanyl citrate
Filgrastim
Fluconazole
Fludarabine phosphate
Foscarnet sodium
Furosemide
Gallium nitrate
Gemcitabine HCl
Granisetron HCl
Heparin sodium
Hetastarch in lactated electrolyte injection (Hextend)
Hydromorphone HCl
Idarubicin HCl
Labetalol HCl
Linezolid
Lorazepam
Melphalan HCl
Meperidine HCl
Methotrexate sodium
Midazolam HCl
Milrinone lactate
Morphine sulfate
Nicardipine HCl
Nitroglycerin
Norepinephrine bitartrate
Ondansetron HCl
Ondansetron HCl with paclitaxel
Ovaliplatin
Paclitaxel
Pancuronium bromide
Pemetrexed disodium
Piperacillin sodium–tazobactam sodium
Procainamide HCl
Propofol
Remifentanil HCl
Sargramostim
Tacrolimus
Teniposide
Theophylline
Thiopental sodium
Thiotepa
Vecuronium bromide
Vinorelbine tartrate
Warfarin sodium
Zidovudine
Incompatible
Amphotericin B cholesteryl sulfate complex
Lansoprazole
Variable
Hetastarch in sodium chloride 0.9%

Inhibits daytime and nocturnal basal gastric acid secretion, stimulated gastric acid secretion.
Competitively inhibits histamine at parietal cell H₂ receptors.

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