Advice to Patients
- Risk of MI or other vasospastic effects; importance of informing clinicians if persistent paresthesia or chest, muscle, or abdominal pain occurs.
- Risk of ergotism; importance of informing clinicians if intermittent claudication; muscle pain; or numbness, coldness, and pallor of the digits occur.
- Importance of taking dihydroergotamine exactly as prescribed.
- Importance of providing patient a copy of manufacturer’s patient information.
- If patient is to administer parenteral dihydroergotamine, provide careful instructions on proper administration methods, including aseptic technique.
- For patients using dihydroergotamine nasal spray, provide careful instruction on pump assembly, priming, and administration.
- Importance of women informing their clinician if they are or plan to become pregnant or plan to breast-feed.
- Importance of informing clinicians of existing or contemplated concomitant therapy, including prescription and OTC drugs, as well as concomitant illnesses.
- Importance of informing patients of other important precautionary information. (See Cautions.)
Preparations
Dihydroergotamine Mesylate
| Routes | Dosage Forms | Strengths | Brand Names | Manufacturer |
|---|
| Intranasal | Solution | 0.5 mg/metered spray (4 mg/mL) |
Migranal® Nasal Spray (with anhydrous caffeine 10 mg/mL; available in ampul with a nasal spray applicator) | Xcel |
| Parenteral | Injection | 1 mg/mL |
D.H.E. 45® (with alcohol 6.1% and glycerin 15%) | Xcel |
Comparative Pricing
This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.
| D.H.E. 45 1MG/ML Solution | VALEANT | 5/$369.3 or 15/$1042.73 |
| Migranal 4MG/ML Solution | VALEANT | 4/$119.99 or 8/$230.98 |
| Migranal 4MG/ML Solution | VALEANT | 6/$294.85 or 18/$824.47 |
AHFS Drug Information. © Copyright, 1959-2008, Selected Revisions September 2004. American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland 20814.
† Use is not currently included in the labeling approved by the US Food and Drug Administration.
Remember, keep this and all other medicines out of the reach of children,
never share your medicines with others, and use this medication only for the indication prescribed.
Print
Email
Save
FDA Alerts
Drug Info Tools
Medicare's drug plans are subsidized by the US federal government and offered through insurers.
