Has been used in the treatment of functional disturbances of GI motility such as irritable bowel syndrome.
Has limited efficacy in the treatment of these disorders and should be used only if other measures (e.g., diet, sedation, counseling, amelioration of environmental factors) have been of little or no benefit.
Has been used in combination with phenobarbital in the treatment of irritable bowel syndrome, but such combined therapy lacks substantial evidence of efficacy.
AcuteEnterocolitis
Has been used alone and in combination with phenobarbital in the treatment of acute enterocolitis†, but the drug alone and the combination lack substantial evidence of efficacy.
Infant Colic
Has been used alone and in combination with phenobarbital in the treatment of infant colic†, but the drug alone and in combination lack substantial evidence of efficacy.
Considered a benign, self-limiting condition that tends to resolve spontaneously and not require medical treatment.
Dosage and Administration
Administration
Administer orally or by IM injection.
Do not administer by IV or subcutaneous injection.
Oral Administration
Usually administer orally.
Dilution
Dilute oral solutions with an equal volume of water just prior to administration.
IM Injection
May be administered by IM injection when oral therapy is not feasible.
Oral therapy should replace IM therapy as soon as possible; do not use IM for longer than 1 or 2 days.
May produce local irritation and/or transient sensation of lightheadedness.
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