Meningococcemia Health Article

Definition

Meningococcemia is an acute and potentially life-threatening infection of the bloodstream that commonly leads to inflammation of the blood vessels (vasculitis).

See also: Septicemia

Alternative Names

Meningococcal septicemia; Meningococcal blood poisoning; Meningococcal bacteremia

Causes, incidence, and risk factors

Meningococcemia is caused by a bacteria called Neisseria meningitidis. The bacteria frequently lives in a person's upper respiratory tract without causing visible signs of illness. The bacteria can be spread from person to person through respiratory droplets -- for example, you may become infected if you are around someone with the condition when they sneeze or cough.

Family members and those closely exposed to someone with the condition are at increased risk. The infection occurs more frequently in winter and early spring.

Symptoms

There may be few symptoms at first. Some may include:

• Anxiety
• Fever
• Irritability
• Spotty red or purple rash (petechiae)

Additional symptoms may include:

• Headache
• Muscle and joint pain
• Nausea
• Vomiting

Later symptoms may include:

• Changing level of consciousness
• Ill appearance
• Large areas of bleeding under the skin (purpura)
• Shock

Signs and tests

Blood tests will be done to rule out other infections and help confirm meningococcemia. Such tests may include:

• Blood culture
• Complete blood count with differential
• Clotting studies (PT, PTT)

Other tests that may be done include:

• Lumbar puncture to obtain spinal fluid sample for CSF culture
• Skin biopsy and gram stain
• Urinalysis

Treatment

Persons with this type of infection are often admitted to the intensive care unit of the hospital, where they are closely monitored. The person may be placed in respiratory isolation for the first 24 hours to help prevent the spread of the infection to others.

Treatments may include:

• Antibiotics given through a vein (IV)
• Breathing support
• Clotting factors or platelet replacement -- if bleeding disorders develop
• Fluids through a vein (IV)
• Medications to treat blood pressure problems
• Wound care for areas of skin with blood clots