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Epidural abscess Health Article

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Definition

An epidural abscess is q collection of pus (infected material) between the outer covering of the brain and spinal cord and the bones of the skull or spine. The abscess causes swelling in the area.

Alternative Names

Abscess - epidural; Spinal abscess

Causes, incidence, and risk factors

Epidural abscess is a rare disorder caused by infection in the area between the bones of the skull or spine, and the membranes covering the brain and spinal cord (meninges). This infection is called an intracranial epidural abscess if it is inside the skull area, or a spinal epidural abscess if it is found in the spine area. Nine out of 10 cases are located in the spine.

The infection is usually caused by bacteria (Staphylococcus aureus is common), but may be caused by fungus. It can be due to other infections in the body, or germs that spread through the blood. However, in up to one-third of patients, no source of infection is found.

In the case of an intracranial epidural abscess (within the skull), risk factors include:

A spinal epidural abscess may be seen in patients with:

  • A history of back surgery or other invasive procedures involving the spine
  • Bloodstream infections
  • Boils
  • Bone infections of the spine (vertebral osteomyelitis)

People who inject drugs are also at increased risk.

Symptoms

Spinal epidural abscess:

Intracranial epidural abscess:

  • Fever
  • Headache
  • Lethargy
  • Nausea and vomiting
  • Pain at the site of recent surgery that gets worse (especially if fever is present)

Neurological symptoms depend on the location of the abscess and may include:

  • Decreased ability to move any part of the body
  • Loss of sensation in any area of the body, or abnormal changes in sensation
  • Paralysis
  • Weakness

Signs and tests

The health care provider will perform an exam to look for a loss of functions such as movement or sensation.

Tests may include:

  • CT scan
  • MRI
  • Sample of the abscess to determine what is causing the infection

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Reviewer Info: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, Unviersity of Washington School of Medicine; and Jatin M. Vyas, PhD, MD, Instructor in Medicine, Harvard Medical School, Assistant in Medicne, Division of Infectious Disease, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.; ADAM Health Illustrated Encyclopedia, 09/28/2008
 
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